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Titolo:
DIFFUSION MEASUREMENTS IN THE ISCHEMIC HUMAN BRAIN WITH A STEADY-STATE SEQUENCE
Autore:
BRUNING R; WU RH; DEIMLING M; PORN U; HABERL RL; REISER M;
Indirizzi:
UNIV MUNICH,KLINIKUM GROSSHADERN,INST RADIOL DIAG,MARCHIONINISTR 15,MRT 1 D-81377 MUNICH GERMANY SIEMENS AG,MED ENGN GRP D-8520 ERLANGEN GERMANY UNIV MUNICH,NEUROL CLIN MUNICH GERMANY
Titolo Testata:
Investigative radiology
fascicolo: 11, volume: 31, anno: 1996,
pagine: 709 - 715
SICI:
0020-9996(1996)31:11<709:DMITIH>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
MIDDLE CEREBRAL-ARTERY; INTRAVOXEL INCOHERENT MOTIONS; ACUTE HUMAN STROKE; FREE PRECESSION; BLOOD-FLOW; MR; PERFUSION; INJURY; RATS; SENSITIVITY;
Keywords:
MAGNETIC RESONANCE IMAGING; DIFFUSION; ISCHEMIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
33
Recensione:
Indirizzi per estratti:
Citazione:
R. Bruning et al., "DIFFUSION MEASUREMENTS IN THE ISCHEMIC HUMAN BRAIN WITH A STEADY-STATE SEQUENCE", Investigative radiology, 31(11), 1996, pp. 709-715

Abstract

RATIONALE AND OBJECTIVES. The authors evaluate the clinical usefulness of a diffusion-weighted steady-state free-precession (SSFP) sequenceto detect acute and subacute ischemic changes. METHODS. Twenty-four patients were examined on a 1.5-tesla scanner, using a SSFP-sequence (repetition time [TR]/echo time [TE] = 22/3-8 mseconds). The slice thickness was 5 mm, 10 averages, 57 seconds per slice, The diffusion gradient strength was 23 millitesla/m, with b-values from 165 to 598 seconds/mm(2), Diffusion-weighted images (DWI) were compared with T2-weightedimages. RESULTS. The diffusion-weighted SSFP sequence produced diagnostic quality images in 23 of 24 patients. Diffusion depicted (group 1:0-12 hours) more acute lesions (3 of 6) than T2-weighted images (2 of6); the mean lesion diameter depicted by diffusion was 10.9 mm (standard deviation [SD], 12.3) and in T2-weighted images was 4.7 mm (SD 6.8), A significant correlation (P < 0.017) in subacute lesions was foundwhen diffusion was compared with turbo spin echo (mean size difference/T2 = 18.5/17.5 mm, SD 13.2/12.2). CONCLUSIONS. The diffusion-weighted SSFP-sequence is more sensitive in acute ischemia and delineates likewise in subacute ischemia, when compared with T2-weighted imaging.

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Documento generato il 11/07/20 alle ore 04:01:43