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Titolo:
CYCLOPHOSPHAMIDE ASSOCIATED BLADDER-CANCER - A HIGHLY AGGRESSIVE DISEASE - ANALYSIS OF 12 CASES
Autore:
FERNANDES ET; MANIVEL JC; REDDY PK; ERCOLE CJ;
Indirizzi:
UNIV MINNESOTA,HOSP & CLIN,DEPT UROL SURG MINNEAPOLIS MN 55455 ST PAUL RAMSEY MED CTR,DEPT UROL ST PAUL MN 55101
Titolo Testata:
The Journal of urology
fascicolo: 6, volume: 156, anno: 1996,
pagine: 1931 - 1933
SICI:
0022-5347(1996)156:6<1931:CAB-AH>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
PATIENTS RECEIVING CYCLOPHOSPHAMIDE; URINARY-BLADDER; LUPUS NEPHRITIS; CARCINOMA; THERAPY; PREVENTION; COMPLICATIONS; SULFONATE; CYSTITIS; MESNA;
Keywords:
BLADDER NEOPLASMS; CARCINOMA; CYCLOPHOSPHAMIDE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
E.T. Fernandes et al., "CYCLOPHOSPHAMIDE ASSOCIATED BLADDER-CANCER - A HIGHLY AGGRESSIVE DISEASE - ANALYSIS OF 12 CASES", The Journal of urology, 156(6), 1996, pp. 1931-1933

Abstract

Purpose: We gained knowledge of the etiology, treatment and prevention of cyclophosphamide associated urothelial cancer. Materials and Methods: The medical records of 6 men and 6 women (mean age 55 years) withcyclophosphamide associated bladder cancer were reviewed. Results: All tumors were grade 3 or 4 transitional cell carcinoma. Of the 5 patients initially treated with endoscopic resection alone only 1 is alive without disease. Of the 6 patients who underwent early cystectomy 4 were alive at 24 to 111 months. The remaining patient with extensive cancer underwent partial cystectomy for palliation and died 3 months later. Conclusions: Cyclophosphamide associated bladder tumor is an aggressive disease. However, long-term survival is possible when radical cystectomy is performed for bladder tumors with any sign of invasion and for recurrent high grade disease, even when noninvasive.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 14/08/20 alle ore 16:55:06