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Titolo:
SEQUENTIAL TRANSARTERIAL CHEMOEMBOLIZATION FOR UNRESECTABLE ADVANCED HEPATOCELLULAR-CARCINOMA
Autore:
JAEGER HJ; MEHRING UM; CASTANEDA F; HASSE F; BLUMHARDT G; LOEHLEIN D; MATHIAS KD;
Indirizzi:
CITY HOSP DORTMUND,DEPT DIAGNOST RADIOL,BEUERHAUSSTR 40 D-44137 DORTMUND GERMANY
Titolo Testata:
Cardiovascular and interventional radiology
fascicolo: 6, volume: 19, anno: 1996,
pagine: 388 - 396
SICI:
0174-1551(1996)19:6<388:STCFUA>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRANSCATHETER OILY CHEMOEMBOLIZATION; ARTERIAL EMBOLIZATION; LIVER RESECTION; IODIZED OIL; CHEMOTHERAPY; MANAGEMENT; INJECTION; CIRRHOSIS; CANCER; TRIAL;
Keywords:
HEPATOCELLULAR CARCINOMA; TRANSARTERIAL CHEMOEMBOLIZATION; PROGNOSTIC FACTORS; SURVIVAL DATA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
32
Recensione:
Indirizzi per estratti:
Citazione:
H.J. Jaeger et al., "SEQUENTIAL TRANSARTERIAL CHEMOEMBOLIZATION FOR UNRESECTABLE ADVANCED HEPATOCELLULAR-CARCINOMA", Cardiovascular and interventional radiology, 19(6), 1996, pp. 388-396

Abstract

Purpose: The aim of this prospective study was to evaluate the feasibility, safety, and efficacy of sequential transarterial chemoembolization (TACE) for patients with unresectable advanced hepatocellular carcinoma (HCC). Methods: Twenty-one consecutive patients with unresectable T3 and T4 HCC were treated by sequential TACE (median time interval between treatments 7 weeks) up to six times with an emulsion of lipiodol, epirubicin, and cisplatin. All TACE procedures were performed as unilobar or whole-liver chemoembolization. Results: An average of 3.9 TACE procedures were performed per patient. One primary and two secondary technical failures occurred. No procedural death was observed. After exclusion of the patient with the primary technical failure and 3 patients with extrahepatic disease, the survival rates for the remaining17 patients at 6, 12, 18, and 24 months were 70.6%, 52.9%, 44.1%, and33.1%, respectively. Conclusion: Sequential TACE is a safe procedure in patients with unresectable advanced HCC and feasible in most cases. It seems to prolong the survival time compared with historical seriesof untreated patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/10/20 alle ore 00:44:13