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Titolo:
IMPULSIVITY AND SEROTONERGIC FUNCTION IN COMPULSIVE PERSONALITY-DISORDER
Autore:
STEIN DJ; TRESTMAN RL; MITROPOULOU V; COCCARO EF; HOLLANDER E; SIEVER LJ;
Indirizzi:
MT SINAI SCH MED,DEPT PSYCHIAT,BOX 1230,1 GUSTAVE LEVY PL NEW YORK NY10029 MT SINAI SCH MED,DEPT PSYCHIAT NEW YORK NY 10029 MED COLL PENN & HAHNEMANN UNIV,EASTERN PENN PSYCHIAT INST PHILADELPHIA PA 19129
Titolo Testata:
The Journal of neuropsychiatry and clinical neurosciences
fascicolo: 4, volume: 8, anno: 1996,
pagine: 393 - 398
SICI:
0895-0172(1996)8:4<393:IASFIC>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
FENFLURAMINE; RESPONSES; PROLACTIN; NEUROENDOCRINE; AGGRESSION; BEHAVIOR;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
24
Recensione:
Indirizzi per estratti:
Citazione:
D.J. Stein et al., "IMPULSIVITY AND SEROTONERGIC FUNCTION IN COMPULSIVE PERSONALITY-DISORDER", The Journal of neuropsychiatry and clinical neurosciences, 8(4), 1996, pp. 393-398

Abstract

This study compared serotonergic function, as assessed by prolactin response to fenfluramine, in males with compulsive personality disorder, males with noncompulsive personality disorders, and normal control subjects. The two patient groups did not differ in age, depression status, suicide history, or comorbid borderline personality disorder. However, compulsive personality disorder patients had significantly greater impulsive aggressive scores than the noncompulsive patients and significantly blunted prolactin responses compared with the non-compulsivepatients anti normal control subjects. In the combined patient group,total compulsive personality disorder traits correlated positively with impulsive aggression score and inversely with prolactin response. These results support the hypothesis that impulsive and compulsive symptoms do not simply lie at opposite ends of a phenomenological and neurobiological spectrum, but rather have a complex intersection and may both correlate with serotonergic dysfunction.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/01/20 alle ore 13:57:59