Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
CATALYTIC ROLE OF THE ALPHA-CARBOXYLATE OF THE GLU RESIDUE OF GLUTATHIONE IN GLUTATHIONE S-TRANSFERASES
Autore:
ZHENG YJ; ORNSTEIN RL;
Indirizzi:
BATTELLE MEM INST,PACIFIC NW LABS,ENVIRONM MOL SCI LAB,MS K2-01 RICHLAND WA 99352 UNIV CALIF SANTA BARBARA,DEPT CHEM SANTA BARBARA CA 93106
Titolo Testata:
Journal of biomolecular structure & dynamics
fascicolo: 2, volume: 14, anno: 1996,
pagine: 231 - 233
SICI:
0739-1102(1996)14:2<231:CROTAO>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
3-DIMENSIONAL STRUCTURE; CRYSTAL-STRUCTURE; RESOLUTION; COMPLEX; ENZYMES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
Y.J. Zheng e R.L. Ornstein, "CATALYTIC ROLE OF THE ALPHA-CARBOXYLATE OF THE GLU RESIDUE OF GLUTATHIONE IN GLUTATHIONE S-TRANSFERASES", Journal of biomolecular structure & dynamics, 14(2), 1996, pp. 231-233

Abstract

The recently proposed catalytic role of the cc-carboxylate of the Gluresidue of glutathione in glutathione S-transferases (Widersten et al, Biochemistry 35, 7731-7742 (1996)) was examined. Based on structuralconsiderations, it is clear that conformational changes in both glutathione and glutathione S-transferase are required. Recent kinetic studies by Ricci and coworkers (Ricci et al, J. Biol. Chem. 271, 16187-16192 (1996) and Caccuri et al, J. Biol. Chem. 271, 16193-16198 (1996)) may provide the missing evidence for these conformational changes. Possible ways to test this hypothesis are discussed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 13:52:53