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Titolo:
COMPENSATORY INCREASE IN COMMON CAROTID-ARTERY DIAMETER - RELATION TOBLOOD-PRESSURE AND ARTERY INTIMA-MEDIA THICKNESS IN OLDER ADULTS
Autore:
POLAK JF; KRONMAL RA; TELL GS; OLEARY DH; SAVAGE PJ; GARDIN JM; RUTAN GH; BORHANI NO;
Indirizzi:
UNIV WASHINGTON,CARDIOVASC HLTH STUDY COORDINATING CTR,1501 4TH ST,SUITE 2105 SEATTLE WA 98101 HARVARD UNIV,BRIGHAM & WOMENS HOSP,SCH MED,DEPT RADIOL BOSTON MA 02115 UNIV CALIF IRVINE,DEPT MED IRVINE CA 92717 UNIV BERGEN,DEPT PUBL HLTH & PRIMARY HLTH CARE BERGEN NORWAY TUFTS UNIV NEW ENGLAND MED CTR,DEPT RADIOL BOSTON MA 02111 NHLBI,DIV EPIDEMIOL & CLIN APPLICAT,EPIDEMIOL & BIOMETRY PROGRAM BETHESDA MD 20892 MEMPHIS VET ADM MED CTR MEMPHIS TN 00000
Titolo Testata:
Stroke
fascicolo: 11, volume: 27, anno: 1996,
pagine: 2012 - 2015
SICI:
0039-2499(1996)27:11<2012:CIICCD>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
LEFT-VENTRICULAR MASS; ESSENTIAL-HYPERTENSION; CARDIOVASCULAR HEALTH; ATHEROSCLEROSIS RISK; CORONARY-ARTERIES; ELASTIC-MODULUS; WALL; ENLARGEMENT;
Keywords:
CAROTID ARTERIES; RISK FACTORS; ULTRASONICS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
J.F. Polak et al., "COMPENSATORY INCREASE IN COMMON CAROTID-ARTERY DIAMETER - RELATION TOBLOOD-PRESSURE AND ARTERY INTIMA-MEDIA THICKNESS IN OLDER ADULTS", Stroke, 27(11), 1996, pp. 2012-2015

Abstract

Background and Purpose Common carotid artery (CCA) diameter is thought to increase as a consequence of hypertension and may increase as thethickness of the arterial wall increases. The purpose of this study was to determine CCA dimensions and correlate them with clinical features. Methods We performed a cross-sectional community-based study of adults 65 years of age and older, measuring inner and outer diameter of the CCA in vivo with carotid sonography. Findings were correlated against risk factors for atherosclerosis, CCA intima-media thickness (IMT), and echocardiographically determined left ventricular (LV) mass. Results Independent variables showing strong positive associations with outer and inner CCA diameter included age, male sex, height. weight, and systolic blood pressure. As an independent variable, LV mass (r = .40 and r = .37, respectively; P < .00001) had a strong positive relation to inner and outer CCA diameters. The relationship between diameter and IMT was different. In a model that controlled for age, sex, and estimated LV mass, an increase of 1 mm in CCA IMT corresponded to a 1.9-mm increase in the outer diameter of the artery (P < .00001) but was not significantly related to the inner diameter (slope = +0.07 mm; P = .26. Conclusions Increase in the outer diameter of the CCA is associated with subject size, sex, age, echocardiographically estimated LV mass, and CCA IMT. Increases in internal diameter of the CCA have similarrelationships but are not related to IMT. This supports the hypothesis that the human CCA dilates as the thickness of the artery wall increases.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 15:45:45