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Titolo:
SCHIZOPHRENIA AND NEUROLOGICAL SOFT SIGNS - GENDER DIFFERENCES IN CLINICAL CORRELATES AND ANTECEDENT FACTORS
Autore:
LANE A; COLGAN K; MOYNIHAN F; BURKE T; WADDINGTON JL; LARKIN C; OCALLAGHAN E;
Indirizzi:
BLACKROCK CO,CLUAIN MHUIRE FAMILY CTR,NEWTOWNPK AVE DUBLIN IRELAND UNIV COLL,DEPT CLIN PHARMACOL DUBLIN IRELAND ROYAL COLL SURGEONS IRELAND,DEPT CLIN PSYCHOL DUBLIN 2 IRELAND ST JOHN OF GOD PSYCHIAT HOSP STILLORGAN DUBLIN IRELAND
Titolo Testata:
Psychiatry research
fascicolo: 2, volume: 64, anno: 1996,
pagine: 105 - 114
SICI:
0165-1781(1996)64:2<105:SANSS->2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
OBSTETRIC COMPLICATIONS; ABNORMALITIES; ONSET; RISK; AGE; SEX; PSYCHOPATHOLOGY; DISCORDANT; NEUROMOTOR; DISORDERS;
Keywords:
SCHIZOPHRENIA NEUROLOGICAL SOFT SIGNS; SEX DIFFERENCES; OBSTETRIC COMPLICATIONS; GENETICS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Citazioni:
44
Recensione:
Indirizzi per estratti:
Citazione:
A. Lane et al., "SCHIZOPHRENIA AND NEUROLOGICAL SOFT SIGNS - GENDER DIFFERENCES IN CLINICAL CORRELATES AND ANTECEDENT FACTORS", Psychiatry research, 64(2), 1996, pp. 105-114

Abstract

Although it is recognized that patients with schizophrenia demonstrate more neurological soft signs (NSS) than control subjects, the significance and clinical correlates of these signs remain poorly defined. The present study examined 48 patients with DSM-III-R schizophrenia forevidence of NSS. The majority (98%) of patients demonstrated at leastone NSS, although the range of scores was wide. There was no relationship between current dosage of neuroleptic medication and NSS score. Among males, there was a significant relationship between NSS and duration of illness. Males whose mothers experienced obstetric complications had higher NSS scores, while females with a family history of schizophrenia exhibited higher scores. These relationships in schizophrenia between NSS and factors of etiological importance such as obstetric complications and family history require further evaluation. The presentfindings are in accord with a body of evidence which suggests that gender may influence the impact of genetic and environmental factors on the neurology of the disorder.

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Documento generato il 31/03/20 alle ore 09:39:50