Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
PROTEASES IN APOPTOSIS
Autore:
ZHIVOTOVSKY B; BURGESS DH; ORRENIUS S;
Indirizzi:
KAROLINSKA INST,DIV TOXICOL,INST ENVIRONM MED,BOX 210 S-17177 STOCKHOLM SWEDEN KAROLINSKA INST,DIV TOXICOL,INST ENVIRONM MED S-17177 STOCKHOLM SWEDEN
Titolo Testata:
Experientia
fascicolo: 10-11, volume: 52, anno: 1996,
pagine: 968 - 978
SICI:
0014-4754(1996)52:10-11<968:PIA>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
TUMOR-NECROSIS-FACTOR; PROGRAMMED CELL-DEATH; INTERLEUKIN-1-BETA CONVERTING-ENZYME; SMALL NUCLEAR RIBONUCLEOPROTEIN; 70-KDA PROTEIN-COMPONENT; BACULOVIRUS P35 PROTEIN; FAS-MEDIATED APOPTOSIS; IL-1-BETA-CONVERTING ENZYME; POLY(ADP-RIBOSE) POLYMERASE; GENE CED-3;
Keywords:
APOPTOSIS; PROTEASES; ICE-LIKE PROTEASES; PROTEIN SUBSTRATES;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
96
Recensione:
Indirizzi per estratti:
Citazione:
B. Zhivotovsky et al., "PROTEASES IN APOPTOSIS", Experientia, 52(10-11), 1996, pp. 968-978

Abstract

The interleukin-1 beta-converting enzyme (ICE)-like family proteases have recently been identified as key enzymes in apoptotic cell death. Among these proteases one can identify specific activities which may be involved in cytokine production or in resident protein cleavage. Several factors influence the constitutive apoptotic mechanism and may provide insight into the role of protease(s) in apoptosis. Although it appears that ICE family members play a most important role in promotingapoptotic cell death, evidence has been advanced that other proteasesare also involved in sequential or parallel steps of apoptosis, Activation of a particular protease dan lead to processing molecules eitherof the same or different proteases, leading to an activation of a protease cascade. Here we attempt to summarize the current thinking concerning these proteases and their involvement in apoptosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 13:09:20