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Titolo:
FUNCTIONAL MR-IMAGING OF SEMANTIC INFORMATION-PROCESSING AND LEARNING-RELATED EFFECTS USING PSYCHOMETRICALLY CONTROLLED STIMULATION PARADIGMS
Autore:
SPITZER M; BELLEMANN ME; KAMMER T; GUCKEL F; KISCHKA U; MAIER S; SCHWARTZ A; BRIX G;
Indirizzi:
UNIV HEIDELBERG,PSYCHIAT KLIN,SEKT EXPT PSYCHOPATHOL D-6900 HEIDELBERG GERMANY UNIV HEIDELBERG,KLINIKUM MANNHEIM,KLIN FAK 2,INST KLIN RADIOL HEIDELBERG GERMANY UNIV HEIDELBERG,KLINIKUM MANNHEIM,KLIN FAK 2,NEUROL KLIN HEIDELBERG GERMANY UNIV MAGDEBURG,NEUROL KLIN D-39106 MAGDEBURG GERMANY DEUTSCH KREBSFORSCHUNGSZENTRUM,FORSCH SCHWERPUNKT RADIOL DIAGNOT & THERAPIE D-6900 HEIDELBERG GERMANY
Titolo Testata:
Cognitive brain research
fascicolo: 3, volume: 4, anno: 1996,
pagine: 149 - 161
SICI:
0926-6410(1996)4:3<149:FMOSIA>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN VISUAL-CORTEX; HUMAN BRAIN; SCHIZOPHRENIC-PATIENTS; SENSORY STIMULATION; CORTICAL AREAS; FRONTAL-CORTEX; MOTOR CORTEX; ACTIVATION; LANGUAGE; ANATOMY;
Keywords:
COGNITIVE NEUROSCIENCE; FUNCTIONAL MAGNETIC RESONANCE IMAGING (FMRI); PSYCHOLINGUISTICS; BRAIN ACTIVATION; LEARNING;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
61
Recensione:
Indirizzi per estratti:
Citazione:
M. Spitzer et al., "FUNCTIONAL MR-IMAGING OF SEMANTIC INFORMATION-PROCESSING AND LEARNING-RELATED EFFECTS USING PSYCHOMETRICALLY CONTROLLED STIMULATION PARADIGMS", Cognitive brain research, 4(3), 1996, pp. 149-161

Abstract

Functional magnetic resonance imaging (fMRI), in conjunction with carefully designed, psychometrically optimized stimulation procedures, was used to investigate the relation between brain activation and the processing of word associations. A semantic discrimination task of word-pair similarity was performed by normal subjects (n=17) within a clinical 1.5-Tesla whole-body MRI system. A color similarity task of psychometrically equivalent difficulty, as indicated by behavioral data acquired online during flc?RI, served as active control condition. Comparisons between tasks dramatically improved results compared to comparisons between task and resting condition. The language paradigm selectively activated left frontal and left fronto-temporal areas. Cortical activation during the semantic task decreased significantly over three runs of the same word list and was paralleled by decreased reaction times. No such changes were observed in the active control condition indicating selective learning of the language task only. When combined withpsychological activation schemes and the acquisition of behavioral data, fMRI represents a powerful tool for the study of brain-behavior interaction.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 04:15:22