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Titolo:
DEVELOPMENT OF PLAGIOCEPHALY IN RABBITS WITH UNICORONAL SYNOSTOSIS
Autore:
BURROWS AM; MOONEY MP; SMITH TD; LOSKEN HW; SIEGEL MI;
Indirizzi:
UNIV PITTSBURGH,DEPT ANTHROPOL,3H01 FORBES QUAD PITTSBURGH PA 15260 UNIV PITTSBURGH,DEPT ANAT & HISTOL PITTSBURGH PA 00000 UNIV PITTSBURGH,DEPT ORTHODONT PITTSBURGH PA 00000 UNIV PITTSBURGH,DEPT PLAST & RECONSTRUCT SURG PITTSBURGH PA 00000 CHILDRENS HOSP PITTSBURGH PITTSBURGH PA 15213 SLIPPERY ROCK UNIV,SCH PHYS THERAPY SLIPPERY ROCK PA 16057
Titolo Testata:
Journal of neurosurgery
fascicolo: 5, volume: 85, anno: 1996,
pagine: 929 - 936
SICI:
0022-3085(1996)85:5<929:DOPIRW>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONAL SUTURE SYNOSTOSIS; FETAL HEAD CONSTRAINT; CRANIOSYNOSTOSIS; GROWTH; CRANIOSTENOSIS; ASYMMETRY; CLOSURE; STRAIN;
Keywords:
PLAGIOCEPHALY; UNICORONAL SYNOSTOSIS; CRANIAL VAULT; RABBIT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
59
Recensione:
Indirizzi per estratti:
Citazione:
A.M. Burrows et al., "DEVELOPMENT OF PLAGIOCEPHALY IN RABBITS WITH UNICORONAL SYNOSTOSIS", Journal of neurosurgery, 85(5), 1996, pp. 929-936

Abstract

Human unicoronal synostosis results in plagiocephaly of the cranial vault due to predictable compensatory growth patterns of the contralateral coronal, sagittal, and ipsilateral squamosal sutures. The present study describes the development of plagiocephaly and tests compensatory growth predictions in a naturally occurring rabbit model of uncorrected unicoronal synostosis. Cranial vault and sutural growth data were collected from serial x-ray films in 70 normal rabbits and 19 rabbits with congenital unicoronal synostosis from 1.5 to 18 weeks of age. One-way analysis of variance results revealed that rabbits with unicoronal synostosis had significant (p < 0.05) growth inhibition at both coronal sutures and the contralateral frontonasal suture and a significantly wider (p < 0.05) cranial vault compared to controls. Paired Student's t-tests between affected and unaffected sides of the vault in rabbits with synostosis revealed significant (p < 0.05) asymmetry, with ipsilateral coronal sutures growing less than contralateral ones. Gross qualitative examination of the adult brains revealed severe asymmetry and anteroposterior reduction on the ipsilateral side. These results demonstrate that this congenital rabbit model effectively simulates human cranial vault growth predictions from unicoronal synostosis and produces a plagiocephalic morphology.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/07/20 alle ore 13:33:29