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Titolo:
BREAST NEOPLASMS - T2-ASTERISK SUSCEPTIBILITY-CONTRAST, FIRST-PASS PERFUSION MR-IMAGING
Autore:
KUHL CK; BIELING H; GIESEKE J; EBEL T; MIELCAREK P; FAR F; FOLKERS P; ELEVELT A; SCHILD HH;
Indirizzi:
UNIV BONN,DEPT RADIOL,SIGMUND FREUD STR 25 D-53105 BONN GERMANY UNIV BONN,DEPT PATHOL D-53105 BONN GERMANY PHILIPS MED SYST HAMBURG GERMANY PHILIPS MED SYST BEST NETHERLANDS
Titolo Testata:
Radiology
fascicolo: 1, volume: 202, anno: 1997,
pagine: 87 - 95
SICI:
0033-8419(1997)202:1<87:BN-TSF>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBRAL BLOOD-VOLUME; TUMOR ANGIOGENESIS; MICROVESSEL DENSITY; PROGNOSTIC-SIGNIFICANCE; VESSEL INVASION; CARCINOMA; MAMMOGRAPHY; LESIONS; BENIGN; DIFFERENTIATION;
Keywords:
BREAST NEOPLASMS, DIAGNOSIS; BREAST NEOPLASMS, MR; GADOLINIUM; MAGNETIC RESONANCE (MR), CONTRAST ENHANCEMENT; MAGNETIC RESONANCE (MR), PERFUSION STUDY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
52
Recensione:
Indirizzi per estratti:
Citazione:
C.K. Kuhl et al., "BREAST NEOPLASMS - T2-ASTERISK SUSCEPTIBILITY-CONTRAST, FIRST-PASS PERFUSION MR-IMAGING", Radiology, 202(1), 1997, pp. 87-95

Abstract

PURPOSE: To evaluate the differentiation of benign from malignant breast tumors with T2-weighted perfusion magnetic resonance (MR) imaging(blood volume imaging) versus that with dynamic T1-weighted contrast agent-enhanced MR imaging. MATERIALS AND METHODS: Ten healthy adult volunteers and 18 adult patients with benign or malignant lesions underwent both conventional T1-weighted dynamic contrast-enhanced breast MR imaging and repetitive first-pass, single-section, dynamic T2-weighted perfusion MR imaging. Images were obtained before, during, and afterinjection of 20 mt of gadopentetate dimeglumine; peak gadopentetate dimeglumine concentrations were calculated from the maximal signal intensity loss on T2-weighted images. RESULTS: No perfusion effect was detectable in healthy breast parenchyma. A strong susceptibility-mediated signal intensity loss occurred in malignant breast tumors. No or only minor perfusion effects were seen in fibroadenomas, in spite of their rapid enhancement at T1-weighted dynamic imaging. Perfusion imaging was possible after conventional dynamic contrast-enhanced breast MR imaging. CONCLUSION T2-weighted perfusion imaging exploits the susceptibility-mediated signal intensity loss of a first-pass bolus of gadopentetate dimeglumine within the capillary bed. First-pass perfusion imaging of breast lesions is feasible. It is promising in the differentiation of benign from malignant, rapidly enhancing lesions.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 05:59:13