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Titolo:
SULCAL, VENTRICULAR, AND WHITE-MATTER CHANGES AT MR-IMAGING IN THE AGING BRAIN - DATA FROM THE CARDIOVASCULAR HEALTH STUDY
Autore:
YUE NC; ARNOLD AM; LONGSTRETH WT; ELSTER AD; JUNGREIS CA; OLEARY DH; POIRIER VC; BRYAN RN;
Indirizzi:
JOHNS HOPKINS UNIV,SCH MED,DEPT RADIOL,600 N WOLFE ST BALTIMORE MD 21287 CARDIOVASC HLTH STUDY COORDINATING CTR SEATTLE WA 00000 UNIV WASHINGTON,DEPT NEUROL SEATTLE WA 98195 UNIV WASHINGTON,DEPT EPIDEMIOL SEATTLE WA 98195 WAKE FOREST UNIV,BOWMAN GRAY SCH MED,DEPT RADIOL WINSTON SALEM NC 00000 UNIV PITTSBURGH,MED CTR,DIV NEURORADIOL PITTSBURGH PA 00000 TUFTS UNIV NEW ENGLAND MED CTR,DEPT RADIOL BOSTON MA 02111 REG DIAGNOST CLEVELAND OH 00000
Titolo Testata:
Radiology
fascicolo: 1, volume: 202, anno: 1997,
pagine: 33 - 39
SICI:
0033-8419(1997)202:1<33:SVAWCA>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBRAL BLOOD-FLOW; COMPUTED-TOMOGRAPHY; NORMAL POPULATION; RISK-FACTORS; AGE; LESIONS; ENLARGEMENT; ATROPHY; DISEASE; ROTTERDAM;
Keywords:
AGING; BRAIN, ANATOMY; BRAIN, ATROPHY; BRAIN, MR;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
36
Recensione:
Indirizzi per estratti:
Citazione:
N.C. Yue et al., "SULCAL, VENTRICULAR, AND WHITE-MATTER CHANGES AT MR-IMAGING IN THE AGING BRAIN - DATA FROM THE CARDIOVASCULAR HEALTH STUDY", Radiology, 202(1), 1997, pp. 33-39

Abstract

PURPOSE: To determine the distribution of changes in sulcal size, ventricular size, and white matter signal intensity depicted on cranial magnetic resonance (MR) images, with stratification according to age, race, and sex. MATERIALS AND METHODS: Ventricular size, sulcal size, and white matter signal intensity changes were graded on cranial MR images of 3,660 community-living, elderly participants in the Cardiovascular Health Study. A healthier subgroup was also defined. Summary statistics for both groups were generated for age, race, and sex. RESULTS: Regression models of the entire imaged cohort showed higher grades of all variables with increasing age, and higher ventricular and sulcal grades in men and in nonblack individuals. White matter grade was greater in women and in black individuals. Regression models of the healthier subgroup showed similar associations, except for a lack of association of sulcal and ventricular size with race. CONCLUSION: Sulcal width,ventricular size, and white matter signal intensity change with age, sex, and race. Knowledge of these changes is important in appropriate interpretation of MR images of the elderly.

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Documento generato il 05/12/20 alle ore 13:58:46