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Titolo:
COMPLETION THYROIDECTOMY IN 131 PATIENTS WITH DIFFERENTIATED THYROID-CARCINOMA
Autore:
SCHEUMANN GFW; SEELIGER H; MUSHOLT TJ; GIMM O; WEGENER G; DRALLE H; HUNDESHAGEN H; PICHLMAYR R;
Indirizzi:
HANNOVER MED SCH,ABDOMINAL & TRANSPLANTAT CHIRURG KLIN D-30623 HANNOVER GERMANY HANNOVER MED SCH,HANNOVER CLIN CANC REGISTRY D-3000 HANNOVER GERMANY HANNOVER MED SCH,DEPT NUCL MED & SPECIAL BIOPHYS D-3000 HANNOVER GERMANY UNIV HALLE WITTENBERG,DEPT GEN SURG D-4010 HALLE GERMANY
Titolo Testata:
The European journal of surgery
fascicolo: 9, volume: 162, anno: 1996,
pagine: 677 - 684
SICI:
1102-4151(1996)162:9<677:CTI1PW>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
CANCER; MANAGEMENT; CHOICE;
Keywords:
THYROID NEOPLASMS; SURGERY; TREATMENT; REOPERATION; SURVIVAL ANALYSIS; NEOPLASM; RECURRENCE; TREATMENT OUTCOME; RETROSPECTIVE STUDIES; PROPORTIONAL HAZARDS MODELS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
28
Recensione:
Indirizzi per estratti:
Citazione:
G.F.W. Scheumann et al., "COMPLETION THYROIDECTOMY IN 131 PATIENTS WITH DIFFERENTIATED THYROID-CARCINOMA", The European journal of surgery, 162(9), 1996, pp. 677-684

Abstract

Objective: To evaluate the prognostic factors that influence survivaland recurrence after ''completion'' thyroidectomy (removal of the total thyroid remnant after diagnosis of carcinoma has been made in a specimen that was incompletely excised for a benign condition). Design: Open study. Setting: Teaching hospital Germany. Subjects: 131 Patients (65 with papillary and 66 with follicular thyroid cancer) who underwent completion thyroidectomy after primary subtotal resection. Interventions: Indications for further operation were: tumour stage worse than pT(1) (n = 116), tumour stage pT(1) and the suspicion of persistence of the tumour (n = 13), and incompletely resected tumour (n = 2). Multivariate analysis by Cox's proportional hazards model. Main outcome measures: Recurrence, development of metastases, and length of survival. Results: Patients who underwent their completion thyroidectomies within six months of the primary operation had significantly fewer recurrences, fewer lymph node metastases, fewer haematogenous metastases and survived significantly longer than those in whom the second operation was delayed for longer than six months. The age at the time of diagnosis and the stage of the tumour influenced survival, whereas sex and type of tumour did not. Conclusion: Completion thyroidectomy as soon as possible after incomplete resection of the tumour may improve prognosisin differentiated thyroid cancers the stage of which is worse than pT(1) or in patients whose recurrent tumour is diagnosed at follow-up.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 11:52:54