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Titolo:
THE STATE OF CAROTID BARORECEPTOR REGULAT ION OF THE CIRCULATION IN PATIENTS WITH ESSENTIAL-HYPERTENSION DURING ADAPTATION TO HIGH-ALTITUDE
Autore:
BITAVRAHIM NI;
Indirizzi:
KYRGYZ CARDIOL RES INST,DEPT ARTERIAL HYPERTENS BISHKEK KYRGYZSTAN
Titolo Testata:
Kardiologia
fascicolo: 8, volume: 36, anno: 1996,
pagine: 56 - 59
SICI:
0022-9040(1996)36:8<56:TSOCBR>2.0.ZU;2-#
Fonte:
ISI
Lingua:
RUS
Keywords:
HYPERTENSION, ESSENTIAL; CAROTID BARORECEPTORS; EXOGENOUS HYPOXIA; MONOAMINERGIC MEDIATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
N.I. Bitavrahim, "THE STATE OF CAROTID BARORECEPTOR REGULAT ION OF THE CIRCULATION IN PATIENTS WITH ESSENTIAL-HYPERTENSION DURING ADAPTATION TO HIGH-ALTITUDE", Kardiologia, 36(8), 1996, pp. 56-59

Abstract

In order to study effects of high altitude hypoxia in carotid baroreceptor regulation of the circulation 27 patients with essential hypertension (hypertensive disease) were subjected to 30 days of ''climatotherapy'' at high altitude. Carotid artery mecganoreceptor sensitivity was tested by the neck chamber technique. Negative pressure (-40 mm Hg) was used for baroreceptor stimulation. Activities of blood serum amineoxidases and platelet monoamineoxidases were also determined. Under background conditions carotid baroreceptors of patients with mild hypertension were characterised by diminished capacity to offset blood pressure rises what was evidenced by decreased systolic and mean blood pressure lowering. Adaptation to high altitude hypoxia resulted in stableblood pressure reduction, decrease if total peripheral resistance, elevation of compliance index of large vessels and significant decrease of arterial impedance. Meanwhile the stay of patients with essential hypertension at high altitude caused development of adaptive resetting of baroreceptors manifested by restoration of initially lowered depressor function of carotid baroreflexes, improvement of vasomotor regulation and suppression of heart rate response to barostimulus. Comparative assessment of monoaminergic mediation revealed decreases of initially elevated values of activity of serum amino oxidases and of platelet monoamine oxidases (p<0,05) thus confirming positive effect of high altitude climatotherapy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 14/07/20 alle ore 10:16:26