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Titolo:
REVERSIBLE SIGNAL ABNORMALITIES IN THE HIPPOCAMPUS AND NEOCORTEX AFTER PROLONGED SEIZURES
Autore:
CHAN S; CHIN SSM; KARTHA K; NORDLI DR; GOODMAN RR; PEDLEY TA; HILAL SK;
Indirizzi:
COLUMBIA UNIV,DEPT RADIOL,MILSTEIN HOSP BLDG,3RD FLOOR,177 FORT WASHINGTON NEW YORK NY 10032 HARLEM HOSP MED CTR,DEPT RADIOL NEW YORK NY 00000 HARLEM HOSP MED CTR,DEPT PATHOL NEW YORK NY 00000 HARLEM HOSP MED CTR,DEPT NEUROL NEW YORK NY 00000 HARLEM HOSP MED CTR,DEPT PEDIAT NEW YORK NY 00000 HARLEM HOSP MED CTR,DEPT NEUROL SURG NEW YORK NY 00000 HARLEM HOSP MED CTR,NEUROL INST NEW YORK NEW YORK NY 00000
Titolo Testata:
American journal of neuroradiology
fascicolo: 9, volume: 17, anno: 1996,
pagine: 1725 - 1731
SICI:
0195-6108(1996)17:9<1725:RSAITH>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
FOCAL STATUS EPILEPTICUS; TEMPORAL-LOBE EPILEPSY; HYPERTENSIVE ENCEPHALOPATHY; SPIN-ECHO; MR; CT;
Keywords:
BRAIN, MAGNETIC RESONANCE; BRAIN, TEMPORAL LOBE; HIPPOCAMPUS; SEIZURES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
S. Chan et al., "REVERSIBLE SIGNAL ABNORMALITIES IN THE HIPPOCAMPUS AND NEOCORTEX AFTER PROLONGED SEIZURES", American journal of neuroradiology, 17(9), 1996, pp. 1725-1731

Abstract

PURPOSE: To investigate the phenomenon of reversible increased signalintensity of medial temporal lobe structures and cerebral neocortex seen on MR images of six patients with recent prolonged seizure activity, METHODS: After excluding patients with known causes of reversible signal abnormalities (such as hypertensive encephalopathy), we retrospectively reviewed the clinical findings and MR studies of six patients whose MR studies showed reversible signal abnormalities. MR pulse sequences included T2-weighted spin-echo coronal views or conventional short-tau inversion-recovery coronal images of the temporal lobes. RESULTS: All six MR studies showed increased signal intensity within the medial temporal lobe, including the hippocampus in five studies. All follow-up MR examinations showed partial or complete resolution of the hyperintensity within the medial temporal lobe and the neocortex. In one patient, results of a brain biopsy revealed severe cerebral cortical gliosis. Temporal lobectomy performed 4 years later showed moderate cortical gliosis and nonspecific hippocampal cell loss and gliosis, CONCLUSION: Significant hyperintensity within the temporal lobe is demonstrable on MR images after prolonged seizure activity, suggestive of seizure-induced edema or gliosis. Damage to medial temporal lobe structures by prolonged seizure activity indicates a possible mechanism of epileptogenic disorders.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/07/20 alle ore 10:26:43