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Titolo:
CIGARETTE-SMOKING AND URINARY ESTROGEN EXCRETION IN PREMENOPAUSAL ANDPOSTMENOPAUSAL WOMEN
Autore:
KEY TJA; PIKE MC; BROWN JB; HERMON C; ALLEN DS; WANG DY;
Indirizzi:
RADCLIFFE INFIRM,IMPERIAL CANC RES FUND,CANC EPIDEMIOL UNIT,GIBSON BLDG OXFORD OX2 6HE ENGLAND UNIV SO CALIF,SCH MED,DEPT PREVENT MED LOS ANGELES CA 90033 UNIV MELBOURNE,DEPT OBSTET & GYNAECOL PARKVILLE VIC 3052 AUSTRALIA IMPERIAL CANC RES FUND LONDON WC2A 3PX ENGLAND ST MARYS HOSP,SCH MED,METAB MED UNIT LONDON W2 1PG ENGLAND
Titolo Testata:
British Journal of Cancer
fascicolo: 8, volume: 74, anno: 1996,
pagine: 1313 - 1316
SICI:
0007-0920(1996)74:8<1313:CAUEEI>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSTMENOPAUSAL WOMEN; STEROID-HORMONES; ESTROGENS; NONSMOKERS; ESTRADIOL; ANDROGEN; SMOKERS; CANCER; RISK;
Keywords:
CIGARETTE SMOKING; URINARY ESTROGEN; ENDOMETRIAL CANCER RISK; EPIDEMIOLOGY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
T.J.A. Key et al., "CIGARETTE-SMOKING AND URINARY ESTROGEN EXCRETION IN PREMENOPAUSAL ANDPOSTMENOPAUSAL WOMEN", British Journal of Cancer, 74(8), 1996, pp. 1313-1316

Abstract

Cigarette smoking is associated with a reduction in the risk for endometrial cancer in postmenopausal women and it has been suggested that this is because smoking has an anti-oestrogenic effect. To investigatethis, concentrations of oestrone, oestradiol and oestriol were measured in 24 h urine samples from 167 premenopausal women (53 smokers, 114non-smokers) and 200 post-menopausal women (54 smokers, 146 non-smokers). Among premenopausal women there were no significant differences in oestrogen excretion between smokers and non-smokers. Among post-menopausal women, geometric mean excretion rates for oestrone and oestradiol did not differ significantly between groups, but oestriol excretionwas 19% lower (95% confidence interval -34% to -1%) in smokers than in non-smokers. This may partly explain the reduced risk for endometrial cancer among post-menopausal smokers.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 06:56:27