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Titolo:
ENTEROPATHOGENS ASSOCIATED WITH CHILDHOOD DIARRHEA IN ITALY
Autore:
CAPRIOLI A; PEZZELLA C; MORELLI R; GIAMMANCO A; ARISTA S; CROTTI D; FACCHINI M; GUGLIELMETTI P; PIERSIMONI C; LUZZI I; MUCIGNAT G; MAGGIO M; GIAMMANCO G; TAORMINA S; VIZZI E; ROMOLI E; SCARDELLATO U;
Indirizzi:
IST SUPER SANITA,BATTERIOL & MICOL MED LAB,VIALE REGINA ELENA 299 I-00161 ROME ITALY IST SUPER SANITA,BATTERIOL & MICOL MED LAB I-00161 ROME ITALY IST SUPER SANITA,LAB VET MED I-00161 ROME ITALY IST SUPER SANITA,LAB ULTRASTRUCT I-00161 ROME ITALY UNIV PALERMO,DEPT HYG & MICROBIOL PALERMO ITALY HOSP R SILVESTRINI PERUGIA ITALY PEDIAT HOSP V BUZZI MILAN ITALY UNIV SIENA,INST INFECT DIS SIENA ITALY GEN HOSP TORRETTE ANCONA ITALY HOSP PORDENONE PORDENONE ITALY UNIV PALERMO PALERMO ITALY HOSP ORVIETO ORVIETO ITALY HOSP TREVISO TREVISO ITALY
Titolo Testata:
The Pediatric infectious disease journal
fascicolo: 10, volume: 15, anno: 1996,
pagine: 876 - 883
SICI:
0891-3668(1996)15:10<876:EAWCDI>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEMOLYTIC-UREMIC SYNDROME; ESCHERICHIA-COLI; CAMPYLOBACTER-JEJUNI; DEVELOPING-COUNTRIES; PERSISTENT DIARRHEA; CHILDREN; TOXIN; INFECTIONS; CRYPTOSPORIDIUM; GASTROENTERITIS;
Keywords:
DIARRHEA; ENTEROPATHOGENS; ETIOLOGY; EPIDEMIOLOGY; ITALY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
49
Recensione:
Indirizzi per estratti:
Citazione:
A. Caprioli et al., "ENTEROPATHOGENS ASSOCIATED WITH CHILDHOOD DIARRHEA IN ITALY", The Pediatric infectious disease journal, 15(10), 1996, pp. 876-883

Abstract

Background. Infectious diarrheal diseases remain an important cause of childhood morbidity in industrialized countries. The knowledge of the etiology and epidemiology of childhood diarrhea in a given area is needed to plan any measure designed to prevent or ameliorate diarrheal illness and to develop practice guidelines for the most appropriate stool examination procedures. Methods. We evaluated 618 children with diarrhea and 135 controls prospectively for viral, bacterial and parasitic enteric pathogens. Diarrheagenic Escherichia coil was identified bygene probes specific to different virulence factors. Stool filtrates were examined for the presence of free bacterial toxins by a cell culture cytotoxicity assay. Clinical and epidemiologic data were recorded and analyzed in relation to microbiologic findings. Results. Enteropathogens were identified in 59% of children with diarrhea and in 10.4% of asymptomatic controls. The agents mainly associated with disease were rotavirus (23.6%), Salmonella (19.2%) and Campylobacter (7.9%). Rotavirus was significantly more frequent among children observed as inpatients whereas Campylobacter was significantly more common in outpatients. Infections with diarrheagenic E. coil, Shigella flexneri, Yersiniaenterocolitica, Cryptosporidium and Giardia were observed in a limited number of patients. The clinical presentation of children was not sufficiently characteristic to permit presumptive diagnosis of a specific pathogen. Conversely the presence of blood and/or leukocytes in stools had a high positive predictive value for Salmonella or Campylobacter infection. Conclusion. The results of this study will be useful for planning strategies to prevent and control diarrheal diseases in our country.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 11:12:40