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Titolo:
LAG PHASE QUANTIFICATION FOR SOLID GASTRIC-EMPTYING STUDIES
Autore:
ZIESSMAN HA; ATKINS FB; VEMULAKONDA US; TALL J; HARKNESS B; FAHEY FH;
Indirizzi:
GEORGETOWN UNIV HOSP,DIV NUCL MED,DEPT RADIOL,3800 RESERVOIR RD WASHINGTON DC 20007 WAKE FOREST UNIV,BOWMAN GRAY SCH MED,PET CTR WINSTON SALEM NC 00000
Titolo Testata:
The Journal of nuclear medicine
fascicolo: 10, volume: 37, anno: 1996,
pagine: 1639 - 1643
SICI:
0161-5505(1996)37:10<1639:LPQFSG>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
LEFT ANTERIOR OBLIQUE; ATTENUATION; LIQUIDS; STOMACH; FOODS; HUMANS; MEALS; SIZE;
Keywords:
RADIONUCLIDE GASTRIC EMPTYING; GASTRIC FUNCTION; LAG PHASE; GASTRIC PHYSIOLOGY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
33
Recensione:
Indirizzi per estratti:
Citazione:
H.A. Ziessman et al., "LAG PHASE QUANTIFICATION FOR SOLID GASTRIC-EMPTYING STUDIES", The Journal of nuclear medicine, 37(10), 1996, pp. 1639-1643

Abstract

This study compared the different calculation methods of the solid gastric emptying lag phase and evaluated the effect of the temporal sampling interval on the calculated value using the modified power exponential (WIPE) method. Methods: Twenty normal control subjects and 42 patients had anterior and posterior image acquisition on a multihead gamma camera, one frame per minute x 90. ROls were selected for the stomach, gastric antrum and small bowel. Time-activity curves (TACs) were generated for anterior, posterior and geometric mean data. The lag phasewas calculated using various methods such as transition point, starting index, first appearance of bower activity (FABA), WIPE and antral peak filling time. To determine the importance of the temporal samplingrate on the calculation of the lag phase by the WIPE, intervals between 1 and 20 min were analyzed. Results: The transition point, startingindex and FABA correlated extremely high (r = greater than or equal to 0.92) in normal control subjects and patients. Normal lag phase values were mean 22-24 +/- 10 min for transition point, starting index andFABA compared with 47 +/- 18 min for the WIPE method (p < 0.0001). The WIPE correlated poorly with the other methods (r = 0.74). Antral peak filling time correlated poorly (r = 0.47) with transition point, starting index and FABA, but somewhat better with the MPE (r = 0.70). Comparing 15-min versus I-min sampling intervals using the WIPE, 35% of subjects had values that differed by greater than or equal to 7.5 min and 10% had values differing by greater than or equal to 15 min. Conclusion: The lag phase calculated by the WIPE correlated poorly with other methods, and its accuracy was limited by the rate of the temporal sampling. The transition point, starting index and FABA all highly correlated with each other; the latter is a particularly reliable physiological indicator and is easily quantified using a small-bowel TAC.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 03:04:22