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Titolo:
LOCALIZATION AND DISTRIBUTION OF VASOACTIVE NEUROPEPTIDES IN THE HUMAN PLACENTA
Autore:
GRAF AH; HUTTER W; HACKER GW; STEINER H; ANDERSON V; STAUDACH A; DIETZE O;
Indirizzi:
SALZBURG GEN HOSP,DEPT OBSTET & GYNAECOL,MUELLNER HAUPTSTR 48 A-5020 SALZBURG AUSTRIA SALZBURG GEN HOSP,INST PATHOL ANAT,IMMUNOHISTOCHEM & BIOCHEM UNIT A-5020 SALZBURG AUSTRIA SALZBURG UNIV,MED RES COORDINAT CTR A-5020 SALZBURG AUSTRIA SUNY DOWNSTATE MED CTR,DEPT PATHOL BROOKLYN NY 00000
Titolo Testata:
Placenta
fascicolo: 7, volume: 17, anno: 1996,
pagine: 413 - 421
SICI:
0143-4004(1996)17:7<413:LADOVN>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
GENE-RELATED-PEPTIDE; HELODERMIN-LIKE PEPTIDES; NEURO-ENDOCRINE CELLS; CO-EXISTENCE; SUBSTANCE-P; CALCITONIN; SILVER; MARKER; IMMUNOREACTIVITY; NORADRENALINE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
72
Recensione:
Indirizzi per estratti:
Citazione:
A.H. Graf et al., "LOCALIZATION AND DISTRIBUTION OF VASOACTIVE NEUROPEPTIDES IN THE HUMAN PLACENTA", Placenta, 17(7), 1996, pp. 413-421

Abstract

Neuropeptides play an important role in the regional regulation of blood flow and hormone secretion. Few studies report the presence of peptides in the human placenta. Our experiment evaluates neuropeptides inthe human placenta using immunocytochemical techniques. Representative tissue sections from full-term placentae were fixed immediately after delivery and processed into paraffin sections or frozen. They were treated with multi pie immunofluorescence, streptavidin-biotin-peroxidase complex and immunogold-silver staining techniques in combination with well-established monoclonal and polyclonal antibodies, using appropriate absorption controls to ensure the validity of the staining. Vasoactive intestinal polypeptide (VIP), calcitonin gene-related peptide (CGRP), neuropeptide tyrosine (NPY), galanin, somatostatin, met-enkephaline, helodermin and substance P-like immunoreactivities were demonstrated within decidual cells. Endothelin-1 was found in both trophoblasts and endothelial cells. Peptide immunoreactivities in the human placenta especially at the decidual interface between mother and fetus supports a role for the diffuse neuroendocrine system (DNES) in the regulation of placental blood flow critical for fetal growth and development. (C) 1996 W. B. Saunders Company Ltd

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 18:46:18