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Titolo:
ALTERED MYOCARDIAL PERFUSION DURING DOBUTAMINE STRESS-TESTING IN SILENT VERSUS SYMPTOMATIC MYOCARDIAL-ISCHEMIA ASSESSED BY QUANTITATIVE MIBI SPET IMAGING
Autore:
ELHENDY A; GELEIJNSE ML; ROELANDT JRTC; CORNEL JH; VANDOMBURG RT; REIJS AEM; NIEROP PR; FIORETTI PM;
Indirizzi:
UNIV HOSP DIJKZIGT,THORAXCTR,BA 300,DR MOLEWATERPLEIN 40 NL-3015 GD ROTTERDAM NETHERLANDS UNIV HOSP DIJKZIGT,THORAXCTR NL-3015 GD ROTTERDAM NETHERLANDS UNIV HOSP DIJKZIGT,DEPT NUCL MED NL-3015 GD ROTTERDAM NETHERLANDS
Titolo Testata:
European journal of nuclear medicine
fascicolo: 10, volume: 23, anno: 1996,
pagine: 1354 - 1360
SICI:
0340-6997(1996)23:10<1354:AMPDDS>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; EMISSION COMPUTED-TOMOGRAPHY; TL-201 EXERCISE TEST; PROGNOSTIC VALUE; UNSTABLE ANGINA; ECHOCARDIOGRAPHY; ISCHEMIA; DYSFUNCTION; ANGIOGRAPHY; REDISTRIBUTION;
Keywords:
SILENT ISCHEMIA; DOBUTAMINE STRESS TEST; METHOXYISOBUTYLISONITRILE SINGLE-PHOTON EMISSION TOMOGRAPHY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
A. Elhendy et al., "ALTERED MYOCARDIAL PERFUSION DURING DOBUTAMINE STRESS-TESTING IN SILENT VERSUS SYMPTOMATIC MYOCARDIAL-ISCHEMIA ASSESSED BY QUANTITATIVE MIBI SPET IMAGING", European journal of nuclear medicine, 23(10), 1996, pp. 1354-1360

Abstract

The aim of the study was to compare the extent and severity of reversible underperfusion in silent versus painful myocardial ischaemia during the dobutamine stress test. A consecutive series of 85 patients with significant coronary artery disease and reversible perfusion defectson technetium-99m methoxyisobutylisonitrile single-photon emission tomography performed at rest and during high-dose dobutamine stress (up to 40 mu g kg(-1) min(-1)) were studied. The left ventricle was divided into six segments. An ischaemic perfusion score was derived quantitatively by subtracting the rest from the stress defect score. Patients with multivessel disease had a higher ischaemic score (610+/-762 vs 310+/-411, P<0.05) and a higher number of reversible perfusion defects (2.1+/-1.2 vs 1.1+/-0.8, P<0.01) than patients with single-vessel disease. Typical angina occurred in 37 patients (44%) during the test. There was no significant difference between patients with and patients without angina with respect to age, gender, peak rate-pressure product, prevalence of previous myocardial infarction, diabetes mellitus, multivessel disease or number of stenotic coronary arteries. Stress, rest and ischaemic scores as well as the number and distribution of reversible defects were not different in patients with and patients without angina. Patients with angina more frequently had a history of typical angina before the test (43% vs 17%, P<0.01) and ST-segment depression during the test (54% vs 25%, P<0.01). It is concluded that in patients with coronary artery disease and ischaemia detected by dobutamine scintigraphy, the extent and severity of coronary artery disease and myocardial perfusion abnormalities are similar with or without angina during stress testing.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/01/20 alle ore 13:58:44