Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
DISTRIBUTION AND GENETIC-HETEROGENEITY OF PUUMALA VIRUS IN SWEDEN
Autore:
HORLING J; LUNDKVIST A; JAAROLA M; PLYUSNIN A; TEGELSTROM H; PERSSON K; LEHVASLAIHO H; HORNFELDT B; VAHERI A; NIKLASSON B;
Indirizzi:
SWEDISH INST INFECT DIS CONTROL S-10521 STOCKHOLM SWEDEN KAROLINSKA INST,CTR MICROBIOL & TUMOR BIOL S-17177 STOCKHOLM SWEDEN UPPSALA UNIV,DEPT GENET S-75007 UPPSALA SWEDEN UNIV HELSINKI,HAARTMAN INST,DEPT VIROL FIN-00014 HELSINKI FINLAND UMEA UNIV,DEPT ANIM ECOL S-90187 UMEA SWEDEN NATL DEF RES ESTAB S-90182 UMEA SWEDEN
Titolo Testata:
Journal of General Virology
, volume: 77, anno: 1996,
parte:, 10
pagine: 2555 - 2562
SICI:
0022-1317(1996)77:<2555:DAGOPV>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
VOLE MONOCLONAL-ANTIBODIES; HEMORRHAGIC-FEVER; RENAL SYNDROME; NEPHROPATHIA EPIDEMICA; MITOCHONDRIAL-DNA; FAMILY BUNYAVIRIDAE; HANTAVIRUS GENUS; ETIOLOGIC AGENT; BANK VOLES; CLETHRIONOMYS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
47
Recensione:
Indirizzi per estratti:
Citazione:
J. Horling et al., "DISTRIBUTION AND GENETIC-HETEROGENEITY OF PUUMALA VIRUS IN SWEDEN", Journal of General Virology, 77, 1996, pp. 2555-2562

Abstract

Small mammals trapped in Sweden were analysed for specific antibody responses against three hantavirus serotypes and for the presence of viral antigen. To determine the genetic identity of viral RNA in lungs of seropositive bank voles (Clethrionomys glareolos), polymerase chain reactions and subsequent partial sequencing of both the M and S segments were employed. The sequences obtained were all identified as Puumala (PUU) virus, with a high degree of heterogeneity between the different geographical localities. Alignment of nucleotide and deduced amino acid sequences, together with phylogenetic analysis, showed that PUU viruses circulating in central Sweden were distinct from those in the northern region. The localization of the two distinct PUU virus genotypes was shown to correlate with the postglacial recolonization of Sweden by bank voles.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/09/20 alle ore 12:55:44