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Titolo:
FUNCTIONAL MAGNETIC-RESONANCE-IMAGING IN THE ACTIVATION OF WORKING-MEMORY
Autore:
SPITZER M; KAMMER T; BELLEMANN ME; GUCKEL F; GEORGI M; GASS A; BRIX G;
Indirizzi:
UNIV HEIDELBERG,PSYCHIAT KLIN,SEKT EXPT PSYCHOPATHOL,VOSSSTR 4 D-69115 HEIDELBERG GERMANY DEUTSCH KREBSFORSCHUNGSZENTRUM,FORSCH SCHWERPUNKT RADIOL DIAGNOST & THERAPIE D-6900 HEIDELBERG GERMANY UNIV HEIDELBERG,INST KLIN RADIOL,KLINIKUM MANNHEIM,KLIN FAK 2 HEIDELBERG GERMANY UNIV HEIDELBERG,NEUROL KLIN,KLINIKUM MANNHEIM,KLIN FAK 2 HEIDELBERG GERMANY
Titolo Testata:
RoFo. Fortschritte auf dem Gebiete der Rontgenstrahlen und der neuenbildgebenden Verfahren
fascicolo: 1, volume: 165, anno: 1996,
pagine: 52 - 58
SICI:
0936-6652(1996)165:1<52:FMITAO>2.0.ZU;2-C
Fonte:
ISI
Lingua:
GER
Soggetto:
PREFRONTAL CORTEX; SENSORY STIMULATION; SCHIZOPHRENIA;
Keywords:
FUNCTIONAL MAGNETIC RESONANCE IMAGING (FMRI); WORKING MEMORY; CORTICAL ACTIVATION; FRONTAL CORTEX;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
39
Recensione:
Indirizzi per estratti:
Citazione:
M. Spitzer et al., "FUNCTIONAL MAGNETIC-RESONANCE-IMAGING IN THE ACTIVATION OF WORKING-MEMORY", RoFo. Fortschritte auf dem Gebiete der Rontgenstrahlen und der neuenbildgebenden Verfahren, 165(1), 1996, pp. 52-58

Abstract

Aims: Functional magnetic resonance imaging was used in conjunction with a letter detection task for the study of working memory in 16 normal subjects. Because of movement artifacts, data from only 9 subjects were analysed. Methods: In the activation task, subjects responded by pressing a button whenever any presented letter was the same as the second last in the sequence. In the control condition, the subjects had to respond to a fixed letter. Hence, the activation condition and the control condition differed only subjectively, i.e., regarding the taskdemand, whereas the stimuli and the type and frequency of response were identical. Results: The activation condition produced significant activation in the dorsolateral prefrontal cortex (Brodmann's areas 10, 46, and 9). Conclusions: In contrast to experimental tasks previously used rather extensively to study the prefrontal cortex, the present paradigm is characterized by its simplicity, interpretability, and its ties to known neurophysiology of the frontal cortex.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/06/20 alle ore 00:53:09