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Titolo:
REGULATION OF VLDL SYNTHESIS AND SECRETION IN THE LIVER
Autore:
GRUFFAT D; DURAND D; GRAULET B; BAUCHART D;
Indirizzi:
INRA,CTR RECH CLERMONT FERRAND THEIX,UNITE RECH METAB ENERGET & LIPIDF-63122 ST GENES CHAMPANE FRANCE
Titolo Testata:
Reproduction, nutrition, development
fascicolo: 4, volume: 36, anno: 1996,
pagine: 375 - 389
SICI:
0926-5287(1996)36:4<375:ROVSAS>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRIGLYCERIDE TRANSFER PROTEIN; LOW-DENSITY-LIPOPROTEIN; FATTY-ACID OXIDATION; APOLIPOPROTEIN-B SECRETION; TOTAL PARENTERAL-NUTRITION; HEP G2 CELLS; MESSENGER-RNA; RAT-LIVER; INTRACELLULAR DEGRADATION; HEPATIC STEATOSIS;
Keywords:
LIVER; TRIACYLGLYCEROL; VLDL SECRETION; REGULATING FACTORS; STEATOSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
87
Recensione:
Indirizzi per estratti:
Citazione:
D. Gruffat et al., "REGULATION OF VLDL SYNTHESIS AND SECRETION IN THE LIVER", Reproduction, nutrition, development, 36(4), 1996, pp. 375-389

Abstract

The production of very low density lipoproteins (VLDL) by the liver results from very complex processes that involve coordinated mechanismsof both protein and lipid synthesis and packaging. Alterations in these metabolic functions can cause negative effects on the health of human subjects or animals. The objectives of this paper were to review the latest developments in the biological mechanisms of these processes and the role of nutritional and hormonal factors. The present study addresses the following issues: i) the main steps in the hepatic metabolism of lipids (long-chain fatty acids, triacylglycerols, phospholipids) and proteins (apolipoprotein B, microsomal transfer protein) primarily involved in the synthesis and secretion of VLDL particles; ii) the metabolic deviations of hepatic VLDL (hypo- and overproduction) in man, rodents and farm animals (poultry, dairy cows).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 21:40:41