Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
OMEPRAZOLE VERSUS HISTAMINE H-2-RECEPTOR ANTAGONISTS IN THE TREATMENTOF ACUTE UPPER NONVARICEAL BLEEDING
Autore:
MOHAMED SA; ALKARAWI MA;
Indirizzi:
ARMED FORCES HOSP,DEPT GASTROENTEROL,A 41,POB 7897 RIYADH 11159 SAUDIARABIA ARMED FORCES HOSP,DEPT GASTROENTEROL RIYADH 11159 SAUDI ARABIA
Titolo Testata:
Hepato-gastroenterology
fascicolo: 10, volume: 43, anno: 1996,
pagine: 863 - 865
SICI:
0172-6390(1996)43:10<863:OVHHAI>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLIND CONTROLLED TRIAL; PEPTIC-ULCER; INTRAVENOUS FAMOTIDINE; TRACT;
Keywords:
OMEPRAZOLE; NONVARICEAL BLEEDING; H-2 RECEPTOR ANTAGONISTS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
S.A. Mohamed e M.A. Alkarawi, "OMEPRAZOLE VERSUS HISTAMINE H-2-RECEPTOR ANTAGONISTS IN THE TREATMENTOF ACUTE UPPER NONVARICEAL BLEEDING", Hepato-gastroenterology, 43(10), 1996, pp. 863-865

Abstract

Background/Aims: To compare the efficacy of omeprazole, a proton pumpinhibitor, with Histamine H-2 receptors antagonists in the control and recurrence of non-variceal zipper gastrointestinal bleeding. Patients and Methods: Seventy-one patients (Group A,Omeprazole) with definitediagnosis of upper gastrointestinal bleeding of non-variceal origin during January 1993-Dec.1994, compared retrospectively with 119 patients (Group B, Ranitidine I with similar criteria during 1987-1993. Patients in, both groups were matched as compared to sex, age and risk factors. Active treatment was omeprazole 40 mg B.D (twice daily) and then orally in, group A compared with ranitidine intravenously 50mg TDS (three times daily) and then. 150mg B.D orally in group B. All patients in both groups had endoscopy at-the time of presentation or within 24 hours. Endoscopic treatment was applied in some of the patients to arrest acute bleeding. The efficacy of treatment was gauged by the number of blood transfusions needed to maintain Hb., evidence of re-bleeding and need for surgery. Results: The patients were well matched for endoscopic diagnosis except duodenal ulcers, which were more common. in group A (P<0.05). In group A out of 71 patients, 5 had rebleeding and 2 required surgery. In group B, out of 119 patients 12 rebled and 10 required surgery. Statistically there was no difference between. groups (p=0.52 by using Kendall's Tau B). Nine patients in omeprazole group received 2 units blood transfusion, 6 patients > 4 units and 3 patients > 6 units, while in the H-2 blocker group, 16 patients received 2 units, 15 patients received > 4 units, and 3 patients > 6 units Of blood transfusion. Statistically there was no-difference between groups with regard to number of transfusions, rebleed or the need for surgery. Conclusions: In our study we found no difference between omeprazole and histamine H-2 receptors antagonists in controlling and recurrence of upper gastrointestinal bleeding.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 04:07:39