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Titolo:
ASSOCIATION BETWEEN INDOOR RESIDENTIAL CONTAMINATION WITH METHYL PARATHION AND URINARY PARA-NITROPHENOL
Autore:
ESTEBAN E; RUBIN C; HILL R; OLSON D; PEARCE K;
Indirizzi:
CTR DIS CONTROL & PREVENT,NATL CTR ENVIRONM HLTH,4770 BUFORD HIGHWAY F46 ATLANTA GA 30341
Titolo Testata:
Journal of exposure analysis and environmental epidemiology
fascicolo: 3, volume: 6, anno: 1996,
pagine: 375 - 387
SICI:
1053-4245(1996)6:3<375:ABIRCW>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
WORKERS;
Keywords:
GEE; MATHEMATICAL MODEL; METHYL PARATHION; ORGANOPHOSPHATE; P-NITROPHENOL; PESTICIDE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
E. Esteban et al., "ASSOCIATION BETWEEN INDOOR RESIDENTIAL CONTAMINATION WITH METHYL PARATHION AND URINARY PARA-NITROPHENOL", Journal of exposure analysis and environmental epidemiology, 6(3), 1996, pp. 375-387

Abstract

Methyl parathion, a pesticide listed by the U.S. Environmental Protection Agency in Toxicity Category I(i.e., most toxic), is not licensed for indoor use, and human exposure has resulted in the deaths of infants and children. From January 1991 through November 1994, an unlicensed pesticide applicator sprayed the interior of more than 200 homes in Lorain County Ohio, with methylparathion. To measure the environmentalcontamination this spraying caused, we measured methyl parathion in residential samples (air filtration and surface wipe) collected from a subset of 64 homes. To measure human exposure, we collected urine samples from 142 people living in these homes and measured urinary levels of para-nitrophenol, a methylparathion metabolite. We then used a generalized estimating equation to evaluate the association between residential contamination and human exposure. The model included the age of the resident, the number of days between pesticide application and sample collection, and air and surface-wipe methyl parathion concentrations. As expected, the air and surface-wipe concentrations each had a significant inverse relationship with the number of days between application and sample collection. The model explained 65.7% of the variationin urinary para-nitrophenol concentrations. The form of this model could be used to estimate urine p-nitrophenol in residents exposed to methyl parathion in situations where urine specimens are not available. We recommend site-specific validation of this model.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 01:15:22