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Titolo:
CHARACTERIZATION OF THE NEWLY CONSTRUCTED DOMAINS THAT REPLACE P5ABC WITHIN THE TETRAHYMENA RIBOZYME
Autore:
IKAWA Y; SHIRAISHI H; INOUE T;
Indirizzi:
KYOTO UNIV,FAC SCI,DEPT CHEM KYOTO 60601 JAPAN KYOTO UNIV,FAC SCI,DEPT CHEM KYOTO 60601 JAPAN
Titolo Testata:
FEBS letters
fascicolo: 1, volume: 394, anno: 1996,
pagine: 5 - 8
SICI:
0014-5793(1996)394:1<5:COTNCD>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
GROUP-I INTRON; RNA; SEQUENCE;
Keywords:
TETRAHYMENA; RIBOZYME; P5ABC; GEL MOBILITY SHIFT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
11
Recensione:
Indirizzi per estratti:
Citazione:
Y. Ikawa et al., "CHARACTERIZATION OF THE NEWLY CONSTRUCTED DOMAINS THAT REPLACE P5ABC WITHIN THE TETRAHYMENA RIBOZYME", FEBS letters, 394(1), 1996, pp. 5-8

Abstract

The P5abc domain of the Tetrahymena ribozyme has been shown to function as an activator that enhances core catalytic activity of the ribozyme. We reported previously that several new domains in that their primary sequences are different from that of P5abc are also capable of activating the ribozyme. It was unclear whether the mechanism of activation by the new domains is identical to that by P5abc. We have investigated structural and functional properties of the new domains and obtained evidence that strongly indicates that a particular domain activatesthe ribozyme in a different manner from that by P5abc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 03:36:14