Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
ANALYSIS OF DEATHS IN PATIENTS AWAITING HEART-TRANSPLANTATION - IMPACT ON PATIENT SELECTION CRITERIA
Autore:
HAYWOOD GA; RICKENBACHER PR; TRINDADE PT; GULLESTAD L; JIANG JP; SCHROEDER JS; VAGELOS R; OYER P; FOWLER MB;
Indirizzi:
STANFORD UNIV,SCH MED,FALK CARDIOVASC RES CTR,DIV CARDIOVASC MED & SURG,300 PASTEUR DR STANFORD CA 94305 STANFORD UNIV,SCH MED,FALK CARDIOVASC RES CTR,DIV CARDIOVASC MED & SURG STANFORD CA 94305
Titolo Testata:
HEART
fascicolo: 5, volume: 75, anno: 1996,
pagine: 455 - 462
SICI:
1355-6037(1996)75:5<455:AODIPA>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
CARDIAC TRANSPLANTATION; OXYGEN-CONSUMPTION; WAITING LIST; SURVIVAL; FAILURE; SUPPORT;
Keywords:
HEART FAILURE; PROGNOSIS; HEART TRANSPLANTATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
G.A. Haywood et al., "ANALYSIS OF DEATHS IN PATIENTS AWAITING HEART-TRANSPLANTATION - IMPACT ON PATIENT SELECTION CRITERIA", HEART, 75(5), 1996, pp. 455-462

Abstract

Objective-To analyse the clinical characteristics of patients who died on the Stanford heart transplant waiting List and to develop a method for risk stratifying status 2 patients (outpatients). Methods-Data were reviewed from all patients over 18 years, excluding retransplants,who were accepted for heart transplantation over an eight year periodfrom 1986 to 1994. Results-548 patients were accepted for heart transplantation; 53 died on the waiting list, and 52 survived on the waiting list for over one year. On multivariate analysis only peak oxygen consumption (peak VO2: 11.7 (SD 2.7) v 15.1 (5.2) ml/kg/min, P = 0.02) and cardiac output (3.97 (1.03) v 4.79 (1.06) litres/min, P = 0.04) were found to be independent prognostic risk factors. Peak VO2 and cardiac index (CI) were then analysed in the last 141 consecutive patients accepted for cardiac transplantation. All deaths and 88% of the deteriorations to status 1 on the waiting list occurred in patients with either a CI < 2.0 or a VO2 < 12. In those with a CI < 2.0 and a VO2 < 12, 38% died or deteriorated to status 1 in the first year on the waiting list. Patients with CI greater than or equal to 2.0 and a VO2 greater than or equal to 12 all survived throughout follow up. Using a Cox's proportional hazards model with CI and peak VO2 as covariates, tables were constructed predicting the chance of surviving for (a) 60 days and(b) 1 year on the waiting list. Conclusions-These data provide a basis for risk stratification of status 2 patients on the heart transplantwaiting list.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 10:48:56