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Titolo:
CARDIOPULMONARY EFFECTS OF RAISED INTRAABDOMINAL PRESSURE BEFORE AND AFTER INTRAVASCULAR VOLUME EXPANSION
Autore:
RIDINGS PC; BLOOMFIELD GL; BLOCHER CR; SUGERMAN HJ;
Indirizzi:
VIRGINIA COMMONWEALTH UNIV,MED COLL VIRGINIA,DEPT SURG,BOX 980519,MCVSTN RICHMOND VA 23298 VIRGINIA COMMONWEALTH UNIV,MED COLL VIRGINIA,DEPT SURG RICHMOND VA 23298
Titolo Testata:
The journal of trauma, injury, infection, and critical care
fascicolo: 6, volume: 39, anno: 1995,
pagine: 1071 - 1075
Fonte:
ISI
Lingua:
ENG
Soggetto:
INCREASED INTRAABDOMINAL PRESSURE; BLOOD-FLOW; ARTERIAL;
Keywords:
ABDOMINAL COMPARTMENT SYNDROME; ABDOMINAL PRESSURE; PLEURAL PRESSURE; HEMODYNAMICS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
P.C. Ridings et al., "CARDIOPULMONARY EFFECTS OF RAISED INTRAABDOMINAL PRESSURE BEFORE AND AFTER INTRAVASCULAR VOLUME EXPANSION", The journal of trauma, injury, infection, and critical care, 39(6), 1995, pp. 1071-1075

Abstract

The cardiopulmonary effects of acutely elevated intra-abdominal pressure (IAP) were studied in a porcine model to help define more clearly IAP effects in patients with trauma, IAP was increased in six anesthetized swine by intra-abdominal instillation of isotonic ethylene glycolup to an IAP of 25 mm Hg above baseline, Systemic and pulmonary hemodynamic parameters were measured, as well as the effects on bladder pressure, pleural pressure, and pulmonary function, At IAP of 25 mm Hg above baseline, intravascular volume expansion with saline was administered to return the cardiac index (CI) to baseline, Raising IAP correlated with measured bladder pressures (r = 0.9, p = 0.001), At IAP of 25 mm Hg, CI was significantly decreased (p < 0.05, analysis of variance (ANOVA); 3.6 +/- 0.3 vs, 2.2 +/- 0.3 L/min/m(2)); whereas wedge, pulmonary arterial, and pleural pressures were all elevated (p < 0.05, ANOVA), However, transarterial wedge pressure (wedge - pleural pressure) declined nonsignificantly with increasing IAP, Raised IAP caused impaired pulmonary function with a decreased (p < 0.05, ANOVA) Pao, and increased (p < 0.05, ANOVA) Paco(2). Despite the elevated wedge pressure, fluid resuscitation returned CI to baseline, These data clarify the hemodynamic changes associated with raised LAP and indicate that care must be taken in interpreting hemodynamic measurements to determine intravascular fluid status in patients with elevated IAP.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/09/20 alle ore 20:00:40