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Titolo:
EFFECT OF POTASSIUM CHANNEL MODULATORS ON MALE SEXUAL-BEHAVIOR
Autore:
BENELLI A; ARLETTI R; POGGIOLI R; CAVAZZUTI E; MAMELI M; BERTOLINI A;
Indirizzi:
UNIV MODENA,PHARMACOL SECT,DEPT BIOMED SCI,VIA G CAMPI 287 I-41100 MODENA ITALY UNIV CAGLIARI,BB BRODIE DEPT NEUROSCI I-09124 CAGLIARI ITALY
Titolo Testata:
Life sciences
fascicolo: 4-5, volume: 60, anno: 1996,
pagine: 263 - 267
SICI:
0024-3205(1996)60:4-5<263:EOPCMO>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
K+ CHANNEL; ANTIDIABETIC SULFONYLUREAS; BINDING-SITES; BRAIN; GLIBENCLAMIDE; LOCALIZATION; OPENERS; RAT;
Keywords:
MALE SEXUAL BEHAVIOR; K-ATP CHANNELS; PINACIDIL GLIBENCLAMIDE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
A. Benelli et al., "EFFECT OF POTASSIUM CHANNEL MODULATORS ON MALE SEXUAL-BEHAVIOR", Life sciences, 60(4-5), 1996, pp. 263-267

Abstract

In the adult sexually experienced male rat, the intracerebroventricular (i.c.v.) injection of pinacidil, a K-ATP channel opener, at the dose of 100 - 150 - 300 mu g/rat worsened the copulatory performance in the presence of a receptive female, whereas the administration of glibenclamide, a K-ATP channel blocker, at the dose of 0.5 and 3 mg/kg intraperitoneally (i.p.) hair an improving effect. These data indicate that K-ATP channels in target neurons my play an important role in the physiology of male sexual behavior.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 04:30:25