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Titolo:
MOLECULAR-CLONING OF A NOVEL RECEPTOR (CMKLR1) WITH HOMOLOGY TO THE CHEMOTACTIC FACTOR RECEPTORS
Autore:
GANTZ I; KONDA Y; YANG YK; MILLER DE; DIERICK HA; YAMADA T;
Indirizzi:
UNIV MICHIGAN,MED CTR,DEPT SURG,6504 MSRB I,1150 W MED CTR DR ANN ARBOR MI 48109 UNIV MICHIGAN,MED CTR,DEPT INTERNAL MED ANN ARBOR MI 48109 UNIV MICHIGAN,MED CTR,DEPT PEDIAT ANN ARBOR MI 48109 UNIV MICHIGAN,MED CTR,DEPT PHYSIOL ANN ARBOR MI 48109
Titolo Testata:
Cytogenetics and cell genetics
fascicolo: 4, volume: 74, anno: 1996,
pagine: 286 - 290
SICI:
0301-0171(1996)74:4<286:MOANR(>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
PROTEIN-COUPLED RECEPTOR; INTERLEUKIN-8 RECEPTOR; HERPESVIRUS SAIMIRI; CHEMOKINE RECEPTORS; AMINO TERMINUS; LIGAND-BINDING; PEPTIDE; DIFFERENTIATION; LOCALIZATION; LEUKOCYTES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
I. Gantz et al., "MOLECULAR-CLONING OF A NOVEL RECEPTOR (CMKLR1) WITH HOMOLOGY TO THE CHEMOTACTIC FACTOR RECEPTORS", Cytogenetics and cell genetics, 74(4), 1996, pp. 286-290

Abstract

We report the cloning of a novel human gene, CMKLR1, which encodes a protein that has notable sequence and structural homology to the seventransmembrane G-protein linked chemokine receptors. This gene has 55%nucleotide sequence homology to the IL-8 type I receptor and 53% to the N-formyl peptide related receptor 1 genes. The mRNA of this receptor is expressed in a broad array of tissues associated with hematopoietic and immune function including, spleen, thymus, appendix, lymph node, bone marrow, and fetal liver. Using fluorescence in situ hybridization the gene encoding CMLKR1 (chemokine-like receptor 1) was localized to human chromosome 12q24.1.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 02:53:56