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Titolo:
ISOLATION AND MAPPING OF RAB2L, A HUMAN CDNA THAT ENCODES A PROTEIN HOMOLOGOUS TO RAIGDS
Autore:
ISOMURA M; OKUI K; FUJIWARA T; SHIN S; NAKAMURA Y;
Indirizzi:
UNIV TOKYO,INST MED SCI,MOL MED LAB,MINATO KU,4-6-1 SHIROKANEDAI TOKYO 108 JAPAN OTSUKA PHARMACEUT CO LTD,OTSUKA GEN RES INST TOKUSHIMA 77101 JAPAN
Titolo Testata:
Cytogenetics and cell genetics
fascicolo: 4, volume: 74, anno: 1996,
pagine: 263 - 265
SICI:
0301-0171(1996)74:4<263:IAMORA>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
NUCLEOTIDE DISSOCIATION STIMULATOR; RAS; IDENTIFICATION; GTPASE; LOCUS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
M. Isomura et al., "ISOLATION AND MAPPING OF RAB2L, A HUMAN CDNA THAT ENCODES A PROTEIN HOMOLOGOUS TO RAIGDS", Cytogenetics and cell genetics, 74(4), 1996, pp. 263-265

Abstract

We have isolated a novel human cDNA, designated RAB2L, that encodes aprotein homologous to Pal guanine nucleotide dissociation stimulator (RalGDS). The predicted sequence of 122 amino acids revealed 39.5% identity with the C-terminal region of human RalGDS. As the C-terminal region of RalCDS is considered to interact with RAS, the product of thisnovel gene may also play some role in the ras-mediated signal transduction pathway. Northern analysis revealed that the gene RAB2L is expressed in all human tissues examined. We assigned this gene locus to chromosome band 6p21.3 by fluorescence in situ hybridization.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 07:02:32