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Titolo:
VACCINE THERAPY FOR MALIGNANT-MELANOMA
Autore:
MORTON DL; BARTH A;
Indirizzi:
ST JOHNS HOSP,JOHN WAYNE CANC INST SANTA MONICA CA 00000
Titolo Testata:
Ca
fascicolo: 4, volume: 46, anno: 1996,
pagine: 225 -
SICI:
0007-9235(1996)46:4<225:VTFM>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACTIVE-SPECIFIC IMMUNOTHERAPY; TUMOR-ASSOCIATED ANTIGEN; CYTOLYTIC T-LYMPHOCYTES; MONOCLONAL-ANTIBODY MK2-23; STAGE-IV MELANOMA; METASTATIC MELANOMA; IMMUNE-RESPONSE; CELL VACCINE; INFILTRATING LYMPHOCYTES; ADJUVANT IMMUNOTHERAPY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
80
Recensione:
Indirizzi per estratti:
Citazione:
D.L. Morton e A. Barth, "VACCINE THERAPY FOR MALIGNANT-MELANOMA", Ca, 46(4), 1996, pp. 225

Abstract

Overall survival for advanced melanoma is extremely poor, and survival with standard therapy has not improved in almost 25 years. Clinical observations suggesting an important role fur the immune system in melanoma have prompted development of experimental approaches using active specific immunotherapy (cancer vaccines). These vaccines may offer apromising new modality for the treatment of malignant melanoma. PhaseII studies have established feasibility, but phase III studies have vet to reveal an unequivocal survival benefit. However, even a minimal therapeutic benefit would be justified by the low toxicity. This article provides an overview of the development of vaccine therapy for malignant melanoma.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 09:45:27