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Titolo:
CENTRAL BRAIN ATROPHY, IN CHILDHOOD AIDS ENCEPHALOPATHY
Autore:
SCARMATO V; FRANK Y; ROZENSTEIN A; LU DF; HYMAN R; BAKSHI S; PAHWA S; PAVLAKIS S;
Indirizzi:
CORNELL UNIV,COLL MED,N SHORE UNIV HOSP,DEPT RADIOL,300 COMMUNITY DR MANHASSET NY 11030 CORNELL UNIV,COLL MED,N SHORE UNIV HOSP,DEPT RADIOL MANHASSET NY 11030 CORNELL UNIV,COLL MED,N SHORE UNIV HOSP,DEPT NEUROL MANHASSET NY 11030 CORNELL UNIV,COLL MED,N SHORE UNIV HOSP,DEPT PEDIAT MANHASSET NY 11030
Titolo Testata:
AIDS
fascicolo: 11, volume: 10, anno: 1996,
pagine: 1227 - 1231
SICI:
0269-9370(1996)10:11<1227:CBAICA>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACQUIRED-IMMUNODEFICIENCY-SYNDROME; IMMUNE-DEFICIENCY SYNDROME; PROGRESSIVE ENCEPHALOPATHY; CEREBRAL ATROPHY; CHILDREN; INFECTION; DEMENTIA; VIRUS; COMPLICATIONS; FEATURES;
Keywords:
AIDS; ATROPHY; PROGRESSIVE ENCEPHALOPATHY; MAGNETIC RESONANCE IMAGING;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
V. Scarmato et al., "CENTRAL BRAIN ATROPHY, IN CHILDHOOD AIDS ENCEPHALOPATHY", AIDS, 10(11), 1996, pp. 1227-1231

Abstract

Objective: To determine differential patterns of brain atrophy in pediatric AIDS encephalopathy. Design: We measured the bicaudate, bifrontal, and ventricle-brain ratio in brain magnetic resonance imaging scans of 42 control children, nine children with progressive AIDS encephalopathy, 25 AIDS children without progressive encephalopathy, and 23 children with cerebral atrophy of other causes. Results: When compared with controls, encephalopathy patients showed significantly increased bicaudate and ventricle-brain ratios, but no significant increase in bifrontal ratio, whereas children with brain atrophy from causes other than AIDS showed increases in all three ratios. Conclusion: Children with AIDS encephalopathy demonstrate a specific pattern of brain atrophydistinct from other etiologies: a central atrophy, primarily affecting the subcortical white matter or the basal ganglia regions.

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Documento generato il 02/12/20 alle ore 18:13:24