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Titolo:
COMPARISON OF THE DEPLOYMENT AND HEALING OF THIN-WALLED EXPANDED PTFESTENTED GRAFTS AND COVERED STENTS
Autore:
WHITE R; KOPCHOK G; ZALEWSKI M; AYRES B; WILSON E; DEVIRGILIO C; DONAYRE C;
Indirizzi:
UNIV CALIF LOS ANGELES,HARBOR MED CTR,DIV VASC SURG,1000 W CARSON ST TORRANCE CA 90509
Titolo Testata:
Annals of vascular surgery
fascicolo: 4, volume: 10, anno: 1996,
pagine: 336 - 346
SICI:
0890-5096(1996)10:4<336:COTDAH>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
AORTIC-ANEURYSM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
10
Recensione:
Indirizzi per estratti:
Citazione:
R. White et al., "COMPARISON OF THE DEPLOYMENT AND HEALING OF THIN-WALLED EXPANDED PTFESTENTED GRAFTS AND COVERED STENTS", Annals of vascular surgery, 10(4), 1996, pp. 336-346

Abstract

This study evaluated the deployment and short-term healing of thin-walled expanded polytetrafluoroethylene (ePTFE) stented grafts and covered stents as endoluminal prostheses in normal canine aortas and in an abdominal aortic aneurysm (AAA) model. Stented grafts consisted of a 7cm length of 3 mm internal diameter ePTFE graft (Impra, Inc., Tempe, Ariz.) with two P-188 Palmaz stents (Johnson & Johnson Interventional Systems, Warren, N.J.) deployed along the inner surface of the ends ofthe graft to secure the prosthesis to the arterial wall. Covered stents were fabricated by placing a 3.7 cm length of 3 mm internal diameter thin-walled ePTFE graft over a P-394 Palmaz stent. Four covered stents and four stented graft prostheses (two of each prototype in the normal canine aorta and AAA model) were implanted in eight animals. One prosthesis of each type in each model was removed at 30 days and one at60 days. Prior to removal, prostheses were evaluated by CT scan, arteriography, and intravascular ultrasound imaging with values compared to those obtained when the prostheses were deployed. Gross inspection and microscopic evaluation were performed at scheduled explantation. Ingeneral, the stented grafts were more difficult to accurately deploy. Healing and maintenance of long-term patency without significant luminal obstruction or occlusion occurred in only one 30-day sample in a normal canine aorta. The 30-day stented graft specimen that had been implanted in an AAA and required the addition of a covered stent to seala maldeployment of the distal segment was also patent. The 60-day stented graft in the normal canine aorta was occluded with narrowing of the graft between the stents. The 60-day stented graft in the AAA was patent with one central fold and thrombus occupying approximately 20% to 30% of the lumen at this site. In contrast, the covered stent devices were less difficult to accurately deploy. All of the covered stent devices were patent with well-incorporated surfaces. Deployment of covered stents was more accurate and less complicated compared to stented grafts. All patent endoluminal prostheses and stent surfaces were wellincorporated into aortic tissues. Problems with graft narrowing, folding, and subsequent thrombosis occurred in the unstented segments of the stented grafts. These preliminary findings support the further development and use of completely supported (stented) devices as endoluminal prostheses.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 10:13:37