Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
IMMUNOEPIDEMIOLOGY OF THE EQUINE TAPEWORM ANOPLOCEPHALA-PERFOLIATA - AGE-INTENSITY PROFILE AND AGE-DEPENDENCY OF ANTIBODY SUBTYPE RESPONSES
Autore:
PROUDMAN CJ; HOLMES MA; SHEORAN AS; EDWARDS SER; TREES AJ;
Indirizzi:
UNIV LIVERPOOL,LIVERPOOL SCH TROP MED,FAC VET SCI,PEMBROKE PL LIVERPOOL L3 5QA MERSEYSIDE ENGLAND UNIV CAMBRIDGE,DEPT VET CLIN SCI CAMBRIDGE CB3 0ES ENGLAND FAC VET SCI,DIV EQUINE STUDIES WIRRAL L64 7TE MERSEYSIDE ENGLAND
Titolo Testata:
Parasitology
, volume: 114, anno: 1997,
parte:, 1
pagine: 89 - 94
SICI:
0031-1820(1997)114:<89:IOTETA>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
PAPUA-NEW-GUINEA; NECATOR-AMERICANUS; INFECTION; HORSES; COMMUNITY; PREVALENCE; ANTIGENS; LESIONS;
Keywords:
ANOPLOCEPHALA PERFOLIATA; EQUINE; AGE DEPENDENCY; IGG SUBTYPES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
C.J. Proudman et al., "IMMUNOEPIDEMIOLOGY OF THE EQUINE TAPEWORM ANOPLOCEPHALA-PERFOLIATA - AGE-INTENSITY PROFILE AND AGE-DEPENDENCY OF ANTIBODY SUBTYPE RESPONSES", Parasitology, 114, 1997, pp. 89-94

Abstract

The equine intestinal cestode Anoplocephala perfoliata has been the subject of recent epidemiological and immunological studies because of its suspected association with intestinal disease in the horse. We have previously shown that the IgG(T) subtype antibody response to the 12/13 kDa component of the parasite excretory/secretory (E/S) antigen ispositively correlated with parasite intensity. In this study, we utilize that correlation to examine the changes in natural infection intensity with age. Infection intensity based on IgG(T) responses showed a triphasic age-dependency pattern with peak mean worm burden in the 6 months-2 years age group, falling to a lower plateau level from 3 to 15years, and rising again in older age groups. Anti-E/S total IgG was found to have a convex age-dependency curve, with maximal response in the 6 months-2 years old age group. IgG(a) showed a triphasic response similar to the age-intensity profile of IgG(T); IgG(c) showed steadilyincreasing levels of antibody with age. The IgG(b) age-dependency profile was intermediate between IgG(a) and IgG(c). Age-specific correlation coeficients between anti-12/13 kDa IgG(T) (as a measure of infection intensity) and IgG(a) and IgG(b) revealed statistically significantvalues for many age groups. The relative importance of exposure to infection and the development of acquired immunity as determinants of the observed age-intensity pattern is considered.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/07/20 alle ore 22:12:52