Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
DEVELOPMENT OF AN IDENTIFIED SPINAL COMMISSURAL INTERNEURON POPULATION IN AN AMNIOTE - NEURONS OF THE AVIAN HOFMANN NUCLEI
Autore:
EIDE AL; GLOVER JC;
Indirizzi:
UNIV OSLO,INST BASIC MED SCI,DEPT PHYSIOL,PB 1103 BLINDERN N-0317 OSLO NORWAY UNIV OSLO,DEPT ANAT N-0317 OSLO NORWAY
Titolo Testata:
The Journal of neuroscience
fascicolo: 18, volume: 16, anno: 1996,
pagine: 5749 - 5761
SICI:
0270-6474(1996)16:18<5749:DOAISC>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
XENOPUS-LAEVIS EMBRYOS; CHICK-EMBRYO; GROWTH CONES; CORD; PROJECTIONS; MECHANISMS; SELECTION; GUIDANCE; PATTERNS; REFLEX;
Keywords:
BIRTHDATING; SPINAL INTERNEURON; NEURONAL MIGRATION; AXON OUTGROWTH; COLLATERAL SPROUTING; SPINAL CORD; CHICKEN EMBRYO;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
38
Recensione:
Indirizzi per estratti:
Citazione:
A.L. Eide e J.C. Glover, "DEVELOPMENT OF AN IDENTIFIED SPINAL COMMISSURAL INTERNEURON POPULATION IN AN AMNIOTE - NEURONS OF THE AVIAN HOFMANN NUCLEI", The Journal of neuroscience, 16(18), 1996, pp. 5749-5761

Abstract

The commissural interneurons of the Hofmann nuclei (HN) of the avian spinal cord (The axonal projections of the Hofmann nuclei in the spinal cord of the late stage chicken embryo, Anat Embryol (Berl), A. L. Eide, 1996, Vol 193, pp 543-557) provide a unique opportunity to describe the development of an identified spinal commissural axon projection and its terminal collaterals in an amniote vertebrate. Here, we use the lipophilic tracer Dil to label these and other commissural projections anterogradely and retrogradely from the time the HN neurons are born. [H-3]lhymidine birthdating shows that the final mitoses of HN neurons occur at stages 21-24 [developmental day (d) 4]. By direct comparison, this follows the generation of motoneurons and of large, dorsally located commissural interneurons. The first HN neurons reach the ventrolateral margin of the spinal cord by d6 by a radial migration throughthe ventral horn. Radial migration occurs after the extension of HN axons across the midline. Thus, HN neurons are determined to be commissural interneurons before attaining their definitive locations. The HN neurons subsequently aggregate into segmentally iterated clusters at the ventrolateral margin of the spinal cord by d8. Also by d8 their longitudinal axons attain mature extent in the ventral funiculus of the contralateral side and begin to sprout collaterals. The collaterals aredirected predominantly toward the medial aspect of the ventral horn at all stages, forming by d12 a dense thicket of terminals that thins out over several segments to each side of the HN of origin. The initialdirection of collateral outgrowth is largely appropriate for the mature termination pattern of the HN. Terminal arbors, however, are less focused at early developmental stages than at later stages.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 15:45:19