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Titolo:
THE 2-WAY PARADIGM OF TRANSPLANTATION IMMUNOLOGY
Autore:
RAO AS; STARZL TE; DEMETRIS AJ; TRUCCO D; THOMSON A; QIAN SG; MURASE N; FUNG JJ;
Indirizzi:
UNIV PITTSBURGH,DEPT SURG,FALK CLIN 5C,3601 5TH AVE PITTSBURGH PA 15213 UNIV PITTSBURGH,MED CTR,PITTSBURGH TRANSPLANT INST PITTSBURGH PA 15213
Titolo Testata:
Clinical immunology and immunopathology
fascicolo: 3, volume: 80, anno: 1996,
parte:, 2
pagine: 46 - 51
SICI:
0090-1229(1996)80:3<46:T2POTI>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
DONOR-CELL CHIMERISM; BONE-MARROW; LIVER-TRANSPLANTATION; ORGAN-TRANSPLANTATION; GRAFT ACCEPTANCE; HOST-CELLS; RECIPIENTS; IMMUNOSUPPRESSION; AUGMENTATION; PROPAGATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
A.S. Rao et al., "THE 2-WAY PARADIGM OF TRANSPLANTATION IMMUNOLOGY", Clinical immunology and immunopathology, 80(3), 1996, pp. 46-51

Abstract

The events following organ transplantation require a reciprocal cell interaction which includes both the conventional host-versus-graft reaction and a graft-versus-host component. With all successful transplantation, both graft and recipient become genetic composites. Where donors were available, chimerism has been confirmed in 30-year kidney-recipient survivors, as well as in several liver and lung recipients. A majority of liver recipients have been able to acquire an immunosuppressant-free state after 10-year survival. Animal models suggest that donor-derived cells may exert a tolerogenic effect. (C) 1996 Academic Press, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/09/20 alle ore 13:39:54