Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
ANXIETY AND AUTONOMIC REGULATION IN MAJOR DEPRESSIVE DISORDER - AN EXPLORATORY-STUDY
Autore:
TULEN JHM; BRUIJN JA; DEMAN KJ; VANDERVELDEN E; PEPPLINKHUIZEN L; TVELD AJMI;
Indirizzi:
UNIV HOSP DIJKZIGT,DEPT PSYCHIAT,DR MOLEWATERPLEIN 40 NL-3015 GD ROTTERDAM NETHERLANDS ERASMUS UNIV ROTTERDAM,SECT PATHOPHYSIOL BEHAV ROTTERDAM NETHERLANDS UNIV HOSP DIJKZIGT,DEPT INTERNAL MED 1 ROTTERDAM NETHERLANDS
Titolo Testata:
Journal of affective disorders
fascicolo: 1-2, volume: 40, anno: 1996,
pagine: 61 - 71
SICI:
0165-0327(1996)40:1-2<61:AAARIM>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEART-RATE-VARIABILITY; POWER-SPECTRAL-ANALYSIS; PANIC DISORDER; PLASMA NOREPINEPHRINE; MYOCARDIAL-INFARCTION; ARTERIAL-PRESSURE; MORTALITY; RESPONSIVITY; MECHANISMS; DISEASE;
Keywords:
MAJOR DEPRESSIVE DISORDER; TRAIT ANXIETY; CARDIOVASCULAR VARIABILITY; SPECTRAL ANALYSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
46
Recensione:
Indirizzi per estratti:
Citazione:
J.H.M. Tulen et al., "ANXIETY AND AUTONOMIC REGULATION IN MAJOR DEPRESSIVE DISORDER - AN EXPLORATORY-STUDY", Journal of affective disorders, 40(1-2), 1996, pp. 61-71

Abstract

Spectral analysis of fluctuations in heart rate and blood pressure was employed to explore sympathetic and parasympathetic cardiovascular control mechanisms in relation to trait anxiety in major depressive disorder. Sixteen drug-free female depressed patients were divided into two groups: those who were high on trait anxiety (HTA, n = 9) and thosewho were normal or low on trait anxiety (LTA, n = 7). In patients andage-matched female controls (n = 10), heart rate (HR), blood pressure(BP; Finapres device) and respiration were recorded during a period of supine rest (10 min), orthostatic challenge (60 degrees head-up tilting, 8 min), and post-orthostatic supine rest (8 min). Power spectra were calculated over the last 4 min of these three situations for HR, systolic BP, as well as for respiration. Spectral density was assessed for three frequency bands: low (0.02-0.06 Hz), mid (0.07-0.14 Hz) and high (0.15-0.50 Hz). Patients did not differ from controls during supine rest. During orthostatic challenge, HTA patients showed significantly more HR increase and suppression of high-frequency fluctuations of HR (suggesting stronger vagal inhibition) in comparison with the controls; this effect was accompanied by a significant increase in respiratory frequency. Both patients groups did not show the normal increase in mid-frequency band fluctuations of BP during orthostatic challenge, indicating reduced sympathetic activation. Low-frequency fluctuations of HR, as well as respiratory frequency during post-orthostatic supinerest of the HTA patients were significantly increased versus controls. This exploratory study indicates that trait anxiety may be a relevant factor when evaluating parasympathetic and sympathetic dysbalances in the state of a major depressive disorder.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 00:11:56