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Titolo:
CORTICAL LOCALIZATION OF HUMAN SUSTAINED ATTENTION - DETECTION WITH FUNCTIONAL MR USING A VISUAL VIGILANCE PARADIGM
Autore:
LEWIN JS; FRIEDMAN L; WU D; MILLER DA; THOMPSON LA; KLEIN SK; WISE AL; HEDERA P; BUCKLEY P; MELTZER H; FRIEDLAND RP; DUERK JL;
Indirizzi:
CASE WESTERN RESERVE UNIV,DEPT RADIOL,11100 EUCLID AVE CLEVELAND OH 44106 CASE WESTERN RESERVE UNIV,DEPT PSYCHIAT CLEVELAND OH 44106 CASE WESTERN RESERVE UNIV,DEPT PSYCHOL CLEVELAND OH 44106 CASE WESTERN RESERVE UNIV,DEPT NEUROL CLEVELAND OH 44106 UNIV HOSP CLEVELAND CLEVELAND OH 44106
Titolo Testata:
Journal of computer assisted tomography
fascicolo: 5, volume: 20, anno: 1996,
pagine: 695 - 701
SICI:
0363-8715(1996)20:5<695:CLOHSA>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN BRAIN; SENSORY STIMULATION; MOTOR CORTEX; ACTIVATION; HANDEDNESS; CONTRAST; SYSTEM;
Keywords:
BRAIN; BRAIN, BLOOD FLOW; BLOOD, FLOW DYNAMICS; MAGNETIC RESONANCE IMAGING;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
28
Recensione:
Indirizzi per estratti:
Citazione:
J.S. Lewin et al., "CORTICAL LOCALIZATION OF HUMAN SUSTAINED ATTENTION - DETECTION WITH FUNCTIONAL MR USING A VISUAL VIGILANCE PARADIGM", Journal of computer assisted tomography, 20(5), 1996, pp. 695-701

Abstract

Purpose: Our goal was to determine whether functional MRI on a standard 1.5 T system can localize activation during a visual vigilance sustained attention task and whether this corresponds to results describedin a PET investigation of a similar task. Method: Sixteen volunteers were studied on a 1.5 T system using a gradient echo technique. A single axial section was oriented within a stereotaxic coordinate space, 40 mm superior to the anterior-posterior commissure line. Images with eyes closed were followed by images during subject concentration on a small dim spot. Motion correction and pixel-by-pixel statistical analysis were performed. Talairach grids were applied for summary statistical analysis and comparison to PET data, with analysis using a series ofplanned contrasts within a repeated measures analysis of variance. Results: Predominantly right-sided frontal and parietal activation was observed, with statistical significance across subjects in the right frontal lobe (F greater than or equal to 5.9, p less than or equal to 0.041). Comparison with previously reported PET data yielded a very similar pattern of activation (F = 13.2; df = 1.8; p = 0.007). Conclusion:Activation of the right middle frontal gyrus and right parietal lobe during visual vigilance is detectable across functional imaging modalities.

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Documento generato il 04/12/20 alle ore 21:25:25