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Titolo:
FLUORESCENT POLYMERASE CHAIN-REACTION OF A PANEL OF CA REPEATS ON CHROMOSOME-6 IN THE INDOLENT PHASE OF FOLLICULAR CENTER CELL LYMPHOMA
Autore:
RANDERSON J; CAWKWELL L; JACK A; LEWIS F; JOHNSON P; EVANS P; BARRANS S; MORGAN GJ;
Indirizzi:
UNIV LEEDS,INST PATHOL,DEPT CLIN SCI PATHOL SCI,ALGERNON FIRTH BLDG LEEDS LS2 9JT W YORKSHIRE ENGLAND UNIV LEEDS,INST PATHOL,DEPT CLIN SCI PATHOL SCI LEEDS LS2 9JT W YORKSHIRE ENGLAND LEEDS GEN INFIRM,HAEMATOL MALIGNANCY DIAGNOST SERV LEEDS W YORKSHIRE ENGLAND LEEDS GEN INFIRM,DEPT MOL PATHOL LEEDS W YORKSHIRE ENGLAND
Titolo Testata:
British Journal of Cancer
fascicolo: 6, volume: 74, anno: 1996,
pagine: 942 - 946
SICI:
0007-0920(1996)74:6<942:FPCOAP>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
NON-HODGKINS-LYMPHOMA; DINUCLEOTIDE REPEAT; ALLELE LOSS; LINKAGE MAP; MICROSATELLITES; POLYMORPHISMS; CARCINOMAS; DEFECTS; CANCER; LOCUS;
Keywords:
FOLLICLE CENTER CELL LYMPHOMA; CHROMOSOME 6; MICROSATELLITE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
J. Randerson et al., "FLUORESCENT POLYMERASE CHAIN-REACTION OF A PANEL OF CA REPEATS ON CHROMOSOME-6 IN THE INDOLENT PHASE OF FOLLICULAR CENTER CELL LYMPHOMA", British Journal of Cancer, 74(6), 1996, pp. 942-946

Abstract

Twenty-four cases of histologically defined follicle centre cell (FCC) lymphoma have been examined for allele imbalance at 19 microsatellite loci spanning the length of chromosome 6, including six markers within the major histocompatibility complex (MHC), using fluorescent polymerase chain reaction (PCR) to amplify microsatellites. Nineteen cases were observed in which imbalance of one or more markers on chromosome 6 had occurred (79%). The frequency of allele imbalance was significantly higher on 6p than 6q, and two regions of deletions, 6p24-25 and 6p21.3-23, were identified in which the loci showed a significantly highallele imbalance frequency.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/09/20 alle ore 11:50:30