Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
NEUROPSYCHOLOGICAL SUBGROUPS OF PATIENTS WITH ALZHEIMERS-DISEASE
Autore:
FISHER NJ; ROURKE BP; BIELIAUSKAS L; GIORDANI B; BERENT S; FOSTER NL;
Indirizzi:
UNIV WINDSOR,DEPT PSYCHOL WINDSOR ON N9B 3P4 CANADA YALE UNIV NEW HAVEN CT 06520 UNIV MICHIGAN ANN ARBOR MI 48109
Titolo Testata:
Neuropsychology, development, and cognition. Section A, Journal of clinical and experimental neuropsychology
fascicolo: 3, volume: 18, anno: 1996,
pagine: 349 - 370
SICI:
1380-3395(1996)18:3<349:NSOPWA>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
PRESENILE-DEMENTIA; CONTROLLED TRIAL; SUBTYPES; PATTERNS; IMPAIRMENT; TOMOGRAPHY; DEFICITS; TACRINE; PROFILE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
85
Recensione:
Indirizzi per estratti:
Citazione:
N.J. Fisher et al., "NEUROPSYCHOLOGICAL SUBGROUPS OF PATIENTS WITH ALZHEIMERS-DISEASE", Neuropsychology, development, and cognition. Section A, Journal of clinical and experimental neuropsychology, 18(3), 1996, pp. 349-370

Abstract

Neuropsychological data from 134 patients diagnosed with probable Alzheimer's disease (AD) were studied retrospectively to investigate whether subgroups of patients with qualitatively distinct profiles could be identified. Three empirical classification approaches were undertaken in this regard: Q-type factor analysis, hierarchical agglomerative cluster analysis, and iterative partitioning. Three subgroups were consistently identified across the clustering methods. Subgroup 1, the largest of the groups, was marked by moderate to severe anemia and constructional dyspraxia. Individuals in subgroup 2 displayed relatively spared visual-perceptual/constructional functioning but severe anemia. Members of subgroup 3 exhibited intact naming and nonverbal reasoning and moderate difficulty in copying overlapping figures. The three subgroups did not differ with respect to age, age at disease onset, durationof illness, educational level, or Hamilton depression rating. Detailed description of the data analyses are provided as a tutorial outlining subtyping methodology. Results are discussed in terms of the subgroup and the stage model approaches to the conceptualization of AD.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 08/07/20 alle ore 05:23:04