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Titolo:
POLYUNSATURATED FATTY-ACID DEFICIENCY IN LIVER-DISEASES - PATHOPHYSIOLOGICAL AND CLINICAL-SIGNIFICANCE
Autore:
CABRE E; GASSULL MA;
Indirizzi:
UNIV BADALONA,HOSP GERMANS TRIAS & PUJOL,DEPT GASTROENTEROL,CARRETERACANYET S-N BADALONA 08916 CATALONIA SPAIN UNIV BADALONA,HOSP GERMANS TRIAS & PUJOL,DEPT GASTROENTEROL BADALONA 08916 CATALONIA SPAIN
Titolo Testata:
Nutrition
fascicolo: 7-8, volume: 12, anno: 1996,
pagine: 542 - 548
SICI:
0899-9007(1996)12:7-8<542:PFDIL->2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
MEMBRANE LIPID-COMPOSITION; RENAL-FUNCTION; HEPATIC-ENCEPHALOPATHY; HEPATORENAL-SYNDROME; CIRRHOTIC-PATIENTS; PLASMA-MEMBRANES; DIETARY-PROTEIN; PROSTAGLANDINS; METABOLISM; LEUKOTRIENES;
Keywords:
POLYUNSATURATED FATTY ACIDS; ESSENTIAL FATTY ACIDS; ARACHIDONIC ACID; EICOSANOIDS; PROSTAGLANDINS; THROMBOXANES; CIRRHOSIS; MEMBRANE FLUIDITY; MALNUTRITION; ALCOHOLISM;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
81
Recensione:
Indirizzi per estratti:
Citazione:
E. Cabre e M.A. Gassull, "POLYUNSATURATED FATTY-ACID DEFICIENCY IN LIVER-DISEASES - PATHOPHYSIOLOGICAL AND CLINICAL-SIGNIFICANCE", Nutrition, 12(7-8), 1996, pp. 542-548

Abstract

Polyunsaturated fatty acid (PUFA) deficiency occurs in advanced cirrhosis and other liver diseases (acute hepatitis, cholestasis). Long-chain PUFA deficit in cirrhosis is due to both essential fatty-acid (EFA)deficiency and impaired PUFA biosynthesis. Although hepatic insufficiency itself mostly accounts for this phenomenon, other factors such asassociated malnutrition also play a role. PUFA deficiency in cirrhosis probably has a wide array of both cellular and clinical consequences, but, at present, they have been difficult to prove. In addition, theroute, dosage, and safety of PUFA supplementation in these patients needs extensive investigation in the future.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 10:34:13