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Titolo:
EFFECTS OF CENTRAL ALPHA-ADRENERGIC AGONISTS ON HORMONE-INDUCED 3-PERCENT NACL AND WATER-INTAKE
Autore:
DEPAULA PM; SATO MA; MENANI JV; DELUCA LA;
Indirizzi:
PAULISTA STATE UNIV,SCH DENT,DEPT PHYSIOL SCI BR-14801903 ARARAQUARA SAO PAULO BRAZIL PAULISTA STATE UNIV,SCH DENT,DEPT PHYSIOL SCI BR-14801903 ARARAQUARA SAO PAULO BRAZIL
Titolo Testata:
Neuroscience letters
fascicolo: 2-3, volume: 214, anno: 1996,
pagine: 155 - 158
SICI:
0304-3940(1996)214:2-3<155:EOCAAO>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
MEDIAN PREOPTIC NUCLEUS; SALT APPETITE; SODIUM APPETITE; 3RD VENTRICLE; ANGIOTENSIN; DRINKING; RAT; LESIONS; REGION;
Keywords:
NORADRENALINE; CLONIDINE; PHENYLEPHRINE; ANGIOTENSIN II; ALDOSTEREONE; ADRENOCEPTORS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
P.M. Depaula et al., "EFFECTS OF CENTRAL ALPHA-ADRENERGIC AGONISTS ON HORMONE-INDUCED 3-PERCENT NACL AND WATER-INTAKE", Neuroscience letters, 214(2-3), 1996, pp. 155-158

Abstract

Male rats received intracerebroventricular (ICV) renin (600 ng) or daily subcutaneous injections of deoxycorticosterone (5 mg) to induce 3%NaCl and water intake. Noradrenaline (NOR; 40-160 nmol) and clonidine(CLO; 5-20 nmol) injected ICV. induced 70 to 100% inhibition of the intakes. Phenylephrine (PHE; 40-160 nmol) injected ICV induced 60 to 95% inhibition of the intakes. NOR and PHE induced a stronger inhibitionon the 3% NaCl intake induced by renin than on the intake induced by deoxycorticosterone (DOC), and CLO did the opposite. CLO was always more effective than PHE to induce inhibition of the intakes. The resultssuggest that NOR inhibits hormone (angiotensin II, aldosterone)-induced NaCl intake by acting mainly on alpha(2)-adrenergic receptors.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 20:10:11