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Titolo:
ARTERIAL-WALL REMODELING AND STIFFNESS IN HYPERTENSION - HETEROGENEOUS ASPECTS
Autore:
LONDON GM; SAFAR ME;
Indirizzi:
HOP FH MANHES,8 GRANDE RUE F-91700 FLEURY MEROGIS FRANCE HOP BROUSSAIS,DEPT INTERNAL MED,INSERM,U337 PARIS FRANCE CLIN MANHES FLEURY MEROGIS FRANCE
Titolo Testata:
Clinical and experimental pharmacology and physiology
fascicolo: 8, volume: 23, anno: 1996,
pagine: 1 - 5
SICI:
0305-1870(1996)23:8<1:ARASIH>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
AGE-RELATED-CHANGES; CAROTID-ARTERY; CARDIAC-HYPERTROPHY; AORTIC COMPLIANCE; WAVE REFLECTIONS; ELASTIC-MODULUS; BLOOD-PRESSURE; CHRONIC UREMIA; RADIAL ARTERY; DISTENSIBILITY;
Keywords:
DISTENSIBILITY; ESSENTIAL HYPERTENSION; LARGE ARTERIES; MEDIUM-SIZED ARTERIES; WALL THICKNESS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
38
Recensione:
Indirizzi per estratti:
Citazione:
G.M. London e M.E. Safar, "ARTERIAL-WALL REMODELING AND STIFFNESS IN HYPERTENSION - HETEROGENEOUS ASPECTS", Clinical and experimental pharmacology and physiology, 23(8), 1996, pp. 1-5

Abstract

1. Hypertension is associated with hypertrophy and decreased operating distensibility of the large artery wall, Because similar pathological and functional changes are observed with ageing, hypertension is often looked upon as an accelerated form of aging. 2. Considering the decrease in arterial distensibility observed with both ageing and hypertension, whether the change is due to age, an increase in distending pressure or to hypertension-induced changes in large artery structural properties may be much debated. 3. The purpose of the present review is to study the effects of aging and hypertension on structural (lumen diameter and arterial wall thickness) and functional (distensibility) properties of large central and medium-sized arteries in humans. 4. Fromclinical studies in subjects with hypertension with or without advanced renal disease, it is suggested that age- and hypertension-induced structural arterial changes are quite heterogeneous, depending on the topography of the vessel and on the severity of the underlying disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 19:43:00