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Titolo:
ASSESSMENT OF DIPYRIDAMOLE-ATROPINE-ECHOC ARDIOGRAPHY FOR THE DETECTION OF RESTENOSIS IN PATIENTS AFTER CORONARY ANGIOPLASTY
Autore:
SCHERHAG A; PFLEGER S; SCHRECKENBERPER A; SIMONIS B; STAEDT U; HEENE DL;
Indirizzi:
UNIV HEIDELBERG,FAK KLIN MED MANNHEIM,MED KLIN 1 D-68135 MANNHEIM GERMANY
Titolo Testata:
Zeitschrift fur Kardiologie
fascicolo: 8, volume: 85, anno: 1996,
pagine: 570 - 579
SICI:
0300-5860(1996)85:8<570:AODAFT>2.0.ZU;2-3
Fonte:
ISI
Lingua:
GER
Soggetto:
DOBUTAMINE STRESS ECHOCARDIOGRAPHY; EFFORT ANGINA-PECTORIS; ARTERY DISEASE; EXERCISE ECHOCARDIOGRAPHY; ASYMPTOMATIC RESTENOSIS; MYOCARDIAL-ISCHEMIA; ELECTROCARDIOGRAPHY; SCINTIGRAPHY; LIMITATIONS; SENSITIVITY;
Keywords:
DIPYRIDAMOLE-ECHOCARDIOGRAPHY; STRESS-ECHOCARDIOGRAPHY; RESTENOSIS; ANGIOPLASTY; PTCA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
47
Recensione:
Indirizzi per estratti:
Citazione:
A. Scherhag et al., "ASSESSMENT OF DIPYRIDAMOLE-ATROPINE-ECHOC ARDIOGRAPHY FOR THE DETECTION OF RESTENOSIS IN PATIENTS AFTER CORONARY ANGIOPLASTY", Zeitschrift fur Kardiologie, 85(8), 1996, pp. 570-579

Abstract

tress-echocardiography has been proven to be a valuable method in thediagnosis of patients with suspected coronary artery disease. It has been demonstrated that the addition of atropine can increase the sensitivity of pharmacological stress-echocardiography-tests. The aim of our study was to evaluate the diagnostic potential of dipyridamole-atropine-echocardiography for the detection of restenosis after coronary angioplasty. We investigated 50 patients 3-6 months after primary successful coronary angioplasty. Restenosis was defined as recurrence of stenosis of greater than or equal to 70% at the site of dilatation determined by quantitative coronary angiography. All patients were investigated on antianginal medication and underwent control-coronary angiography within 1-3 days after the echocardiographic study. In 17/23 patients with restenosis, the dipyridamole-atropine-stress-test was pathologic (sensitivity 74%), in 25/27 patients without significant restenosis the echocardiography stress-test was normal (specificity 93%). In 6 patients with restenosis and an unsuspicious stress-test, the percent diameter of restenosis did not exceed greater than or equal to 90% lumennarrowing, restenosis of the LAD was correctly identified in all patients (n = 11). The diagnostic accuracy of the dipyridamole-atropine-stress-test for the detection of patients with restenosis after PTCA in our study was 84%: the positive predictive value of a pathologic echocardiography stress-test for the detection of significant restenosis was 89%, the negative predictive value was 81%. Conclusions: Dipyridamole-atropine-echocardiography has diagnostic potential for non-invasive assessment of patients after coronary angioplasty. In patients with a normal echocardiographic stress-test, the probability of significant restenosis is considerably low, even if restenosis cannot be definitelyexcluded.

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Documento generato il 05/07/20 alle ore 00:20:37