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Titolo:
INHIBITORY-ACTION OF NOCICEPTIN ON SPINAL DORSAL HORN NEURONS OF THE RAT, IN-VIVO
Autore:
STANFA LC; CHAPMAN V; KERR N; DICKENSON AH;
Indirizzi:
UNIV LONDON UNIV COLL,DEPT PHARMACOL,GOWER ST LONDON WC1E 6BT ENGLAND
Titolo Testata:
British Journal of Pharmacology
fascicolo: 8, volume: 118, anno: 1996,
pagine: 1875 - 1877
SICI:
0007-1188(1996)118:8<1875:IONOSD>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
RECEPTOR; OPIOIDS;
Keywords:
NOCICEPTIN; ANTINOCICEPTION; SPINAL CORD; WIND-UP; C-FIBERS; NALOXONE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
8
Recensione:
Indirizzi per estratti:
Citazione:
L.C. Stanfa et al., "INHIBITORY-ACTION OF NOCICEPTIN ON SPINAL DORSAL HORN NEURONS OF THE RAT, IN-VIVO", British Journal of Pharmacology, 118(8), 1996, pp. 1875-1877

Abstract

Intrathecally administered nociceptin (5, 50, 225 mu g) dose-relatedly inhibited the C-fibre evoked wind-up and post-discharge of dorsal horn neurones, but not the baseline C-fibre evoked responses. Spinal naloxone 50 mu g, but not 10 mu g, reversed the effects of nociceptin. Thus the antinociceptive role of nociceptin in the spinal cord differs from that of classical opioids.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 14:40:40