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Titolo:
10-YEAR EXPERIENCE WITH PRENATAL INTERVENTION FOR HYDRONEPHROSIS
Autore:
COPLEN DE; HARE JY; ZDERIC SA; CANNING DA; SNYDER HM; DUCKETT JW;
Indirizzi:
CHILDRENS HOSP PHILADELPHIA,DIV UROL PHILADELPHIA PA 19104 PENN HOSP,DIV MATERNAL FETAL MED PHILADELPHIA PA 19107
Titolo Testata:
The Journal of urology
fascicolo: 3, volume: 156, anno: 1996,
pagine: 1142 - 1145
SICI:
0022-5347(1996)156:3<1142:1EWPIF>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
FETAL OBSTRUCTIVE UROPATHY; URINARY-TRACT OBSTRUCTION; CONGENITAL HYDRONEPHROSIS; RENAL DYSPLASIA; INUTERO; ELECTROLYTES; SURGERY; SHUNTS;
Keywords:
KIDNEY; HYDRONEPHROSIS; FETUS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
D.E. Coplen et al., "10-YEAR EXPERIENCE WITH PRENATAL INTERVENTION FOR HYDRONEPHROSIS", The Journal of urology, 156(3), 1996, pp. 1142-1145

Abstract

Purpose: We evaluated clinical outcomes after attempted prenatal intervention in fetuses with hydronephrosis. Materials and Methods: We retrospectively reviewed the histories of 10 fetuses considered for prenatal intervention between 1984 and 1993. One female and 8 male fetuses had bilateral hydroureteronephrosis and profound or progressive oligohydramnios, and 1 male fetus had massive progressive unilateral hydronephrosis. Results: Shunt placement was not recommended and it was refused by the parents in 1 case each. Amniotic shunting was attempted in 8fetuses between 22 and 28 weeks of gestation. Shunts were successfully placed with decreased hydronephrosis and increased amniotic fluid volume in 4 cases, while shunt placement was not technically possible inthe remainder. Two shunts that retracted intra-abdominally at birth required laparotomy for retrieval. Postnatally all patients with shuntshad compromised renal function. Of the 4 patients in whom attempts were unsuccessful 3 had mildly diminished renal function and 1 died of nonrenal causes (intraabdominal sepsis) on day 16 of life. No patient with a functioning shunt had postnatal pulmonary problems, whereas 3 without successful intervention had mild respiratory compromise. Conclusions: No definite advantage was noted in the small number of fetuses that underwent successful shunting. Successful shunt placement did not prevent renal insufficiency. The relief of oligohydraminos may benefitpulmonary function in some patients. The high technical failure and complication rates of in utero intervention should be considered beforeproceeding.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/10/20 alle ore 07:15:17