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Titolo:
MALIGNANT ECTOMESENCHYMOMA IN CHILDHOOD
Autore:
MOUTON SCE; ROSENBERG HS; COHEN MC; DRUT R; EMMS M; KASCHULA ROC;
Indirizzi:
RED CROSS CHILDRENS HOSP,DEPT PATHOL ZA-7700 RONDEBOSCH SOUTH AFRICA UNIV CAPE TOWN ZA-7700 RONDEBOSCH SOUTH AFRICA HOSP NINOS SOR MARIA LUDOVICA,DEPT PATHOL LA PLATA ARGENTINA UNIV TEXAS,DEPT PATHOL & LAB MED HOUSTON TX 00000
Titolo Testata:
PEDIATRIC PATHOLOGY & LABORATORY MEDICINE
fascicolo: 4, volume: 16, anno: 1996,
pagine: 607 - 624
SICI:
1077-1042(1996)16:4<607:MEIC>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
ROUND-CELL TUMORS; DIVERGENT DIFFERENTIATION; SOFT-TISSUES; RHABDOMYOSARCOMA; GANGLIORHABDOMYOSARCOMA; CYTOKERATIN; EXPRESSION; NEOPLASMS; PROTEIN; MUSCLE;
Keywords:
CHILDHOOD; MALIGNANT ECTOMESENCHYMOMA; SOFT TISSUES;
Tipo documento:
Article
Natura:
Periodico
Citazioni:
24
Recensione:
Indirizzi per estratti:
Citazione:
S.C.E. Mouton et al., "MALIGNANT ECTOMESENCHYMOMA IN CHILDHOOD", PEDIATRIC PATHOLOGY & LABORATORY MEDICINE, 16(4), 1996, pp. 607-624

Abstract

Five childhood malignant ectomesenchymomas are reported from three centers in three countries. The children were all younger than 3 gears (four less than 12 months), four were boys, and four tumors were sited in the pelvis or external genitalia. All tumors had distinctive light microscopic features of rhabdomyosarcoma and three also demonstrated small numbers of included neuronal cells. Immunohistochemical studies and transmission electron microscopy revealed the additional presence of neurogenic components in the remaining two patients. An additional epithelial component was found by immunohistochemistry in one tumor, which suggests a pluripotential origin that still requires karyotypic investigation. Aggressive chemotherapy and adequate surgical excision. have thus far been effective in providing disease-free follow-up for periods of 7 to 50 months. It is implied that because the biological behavior and morphology closely resemble those of rhabdomyosarcoma and because the neurogenic component is often inconspicuous, mag malignant ectomesenchymomas may be misdiagnosed as rhabdomyosarcomas.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 05:39:08