Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
CHARACTERIZATION OF A PORPHYROMONAS-GINGIVALIS GENE PRTR THAT ENCODESAN ARGININE-SPECIFIC THIOL PROTEINASE AND MULTIPLE ADHESINS
Autore:
SLAKESKI N; CLEAL SM; REYNOLDS EC;
Indirizzi:
UNIV MELBOURNE,SCH DENT SCI,BIOCHEM & MOL BIOL UNIT,711 ELIZABETH ST MELBOURNE VIC 3000 AUSTRALIA UNIV MELBOURNE,SCH DENT SCI,BIOCHEM & MOL BIOL UNIT MELBOURNE VIC 3000 AUSTRALIA
Titolo Testata:
Biochemical and biophysical research communications
fascicolo: 3, volume: 224, anno: 1996,
pagine: 605 - 610
SICI:
0006-291X(1996)224:3<605:COAPGP>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLACK-PIGMENTED BACTEROIDES; CYSTEINE PROTEINASE; STRUCTURAL CHARACTERIZATION; NUCLEOTIDE-SEQUENCE; MOLECULAR-CLONING; PURIFICATION; W50; PROTEASE; BACTEROIDES-GINGIVALIS-W50; PERIODONTITIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
34
Recensione:
Indirizzi per estratti:
Citazione:
N. Slakeski et al., "CHARACTERIZATION OF A PORPHYROMONAS-GINGIVALIS GENE PRTR THAT ENCODESAN ARGININE-SPECIFIC THIOL PROTEINASE AND MULTIPLE ADHESINS", Biochemical and biophysical research communications, 224(3), 1996, pp. 605-610

Abstract

Cysteine proteinases of Porphyromonas gingivalis have been implicatedas major virulence factors in the development of periodontitis. Several groups have reported the characterisation of similar genes encodingthe same arginine-specific thiol proteinase from P. gingivalis; however, the reported size and structure of the genes have varied. We report here the complete nucleotide sequence of the gene prtR that encodes a polyprotein containing the Arg-specific proteinase and multiple haemagglutinins/adhesins. The nascent polyprotein consists of a putative leader sequence and a prosequence followed by the 45 kDa Arg-specific proteinase and 44, 15, 17 and 27 kDa sequence-related adhesins in that order. The size and structure of the prtR are consistent with the sizeof the mRNA transcript (5.3 kb) and the size and sequences of the individual protein components purified from P. gingivalis. (C) 1996 Academic Press, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 00:10:40