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Titolo:
IMMUNOHISTOCHEMICAL ANALYSIS OF ANDROGEN RECEPTOR IN THE ABDOMINAL GLANDS OF THE CLOACA OF MALE RED-BELLIED NEWTS, CYNOPS-PYRRHOGASTER
Autore:
MATSUMOTO A; ARAI Y; TOYODA F; KIKUYAMA S; PRINS GS;
Indirizzi:
JUNTENDO UNIV,SCH MED,DEPT ANAT TOKYO 113 JAPAN NARA MED UNIV,DEPT PHYSIOL KASHIHARA NARA 634 JAPAN WASEDA UNIV,SCH EDUC,DEPT BIOL TOKYO 16950 JAPAN UNIV ILLINOIS,COLL MED,DEPT UROL CHICAGO IL 60612
Titolo Testata:
Zoological science
fascicolo: 3, volume: 13, anno: 1996,
pagine: 429 - 433
SICI:
0289-0003(1996)13:3<429:IAOARI>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
CRESTED NEWT; PROLACTIN; PROSTATE; TESTOSTERONE; SEX; PHEROMONE; INDUCTION; BEHAVIOR; GENES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
40
Recensione:
Indirizzi per estratti:
Citazione:
A. Matsumoto et al., "IMMUNOHISTOCHEMICAL ANALYSIS OF ANDROGEN RECEPTOR IN THE ABDOMINAL GLANDS OF THE CLOACA OF MALE RED-BELLIED NEWTS, CYNOPS-PYRRHOGASTER", Zoological science, 13(3), 1996, pp. 429-433

Abstract

Androgen receptor immunoreactivity was examined in the abdominal glands of the cloaca in adult male red-bellied newts, Cynops pyrrhogaster,using a polyclonal anti-androgen receptor antibody, PG21. In castrated males treated with saline, prolactin, testosterone propionate or both prolactin and testosterone propionate, all displayed androgen receptor immunostaining of nuclei in the epithelial cells of the glands. Androgen receptor-immunoreactive signals were distributed uniformly in the nuclei in the castrates treated with saline or prolactin. On the other hand, the signals were distributed reticulately in the nuclei in the castrates treated with testosterone propionate or both prolactin andtestosterone propionate. Following treatment with testosterone propionate or both prolactin and testosterone propionate, shape of the androgen receptor-immunoreactive nuclei was altered from nonspherical profiles toward spherical profiles and its size became increased. There were no differences in these changes between the testosterone propionate-and both prolactin and testosterone propionate-treated castrates. These findings suggest that androgen participates in regulating size and shape of the nuclei and distribution of androgen receptor in the nuclei of the epithelial cells of the abdominal glands of male newts and that the structural reorganization is necessary for gene expression under the influence of androgen.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 09:25:22